SCHEMBL24390194

SCHEMBL24390194

CCC(CC)COC(=O)/C(C#N)=C/C=C1\Sc2ccccc2N1CC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 11/20 0.56
▸ MEN1 O00255 10/20 0.56
▸ KMT2A Q03164 10/20 0.56
▸ ALDH1A1 P00352 9/20 0.56
▸ USP2 O75604 5/20 0.56
▸ CRHBP P24387 3/20 0.56
▸ CRHR2 Q13324 3/20 0.56
▸ HPGD P15428 2/20 0.56
▸ IDE P14735 1/20 0.54
▸ RAB9A P51151 4/20 0.53
▸ LMNA P02545 3/20 0.53
▸ SMN1; SMN2 Q16637 2/20 0.53
▸ MAPK1 P28482 4/20 0.49
▸ L3MBTL1 Q9Y468 1/20 0.49
▸ FNTA P49354 7/20 0.48
▸ FNTB P49356 7/20 0.48
▸ HTT P42858 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.41
▸ TP53 P04637 1/20 0.41
▸ POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24390191 0.89 FNTA (0.49) MAPTMEN1KMT2AALDH1A1USP2
SCHEMBL24390185 0.89 MAPT (0.70) MAPTMEN1KMT2AALDH1A1USP2
SCHEMBL10036074 0.86 MAPT (0.61) MAPTMEN1KMT2AALDH1A1USP2
SCHEMBL14437578 0.77 MEN1 (0.58) MAPTMEN1KMT2AALDH1A1USP2
SCHEMBL24390187 0.77 FNTA (0.60) MAPTMEN1KMT2AALDH1A1USP2
SCHEMBL11851144 0.76 MEN1 (0.64) MAPTMEN1KMT2AALDH1A1USP2
SCHEMBL14437580 0.76 MEN1 (0.61) MAPTMEN1KMT2AALDH1A1USP2
SCHEMBL11320980 0.74 MEN1 (0.89) MAPTMEN1KMT2AALDH1A1USP2
SCHEMBL14582149 0.74 MEN1 (0.46) MAPTMEN1KMT2AALDH1A1USP2
SCHEMBL14582207 0.74 MEN1 (0.46) MAPTMEN1KMT2AALDH1A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220137260-A1 POLYMERIZABLE COMPOSITION, COMPOUND, POLYMER, RESIN COMPOSITION, ULTRAVIOLET CUT FILM, AND LAMINATE FUJIFILM CORPORATION (JP) 2022-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220137260-A1 POLYMERIZABLE COMPOSITION, COMPOUND, POLYMER, RESIN COMPOSITION, ULTRAVIOLET CUT FILM, AND LAMINATE RER1, C5, RAD51 MAPT 1441/4885MEN1 1611/4885KMT2A 2985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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