Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29937566 | 1.00 | MRGPRX4 (0.44) | MRGPRX4EPHX2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL31168086 | 0.88 | MRGPRX4 (0.44) | MRGPRX4EPHX2KDM4EBACE1GAA | |
| SCHEMBL12818154 | 0.88 | MRGPRX4 (0.46) | MRGPRX4EPHX2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL26612154 | 0.86 | POLB (0.46) | KDM4EPOLBALDH1A1HPGD | |
| SCHEMBL13201484 | 0.85 | MAPT (0.44) | EPHX2KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8232877 | 0.85 | CYP2C9 (0.54) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL149036 | 0.84 | KDM4E (0.55) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25253763 | 0.82 | KDM4E (0.36) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL21994382 | 0.82 | KDM4E (0.44) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1435026 | 0.81 | CFTR (0.57) | MRGPRX4KDM4ECYP2C19KMT2ACFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12538924-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | SYNGENTA CROP PROTECTION AG (CH) | 2026-02-03 | — | — | US | disclosed |
| EP-4204409-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2025-12-24 | — | — | EP | disclosed |
| US-20240018128-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2024-01-18 | — | — | US | disclosed |
| US-20240018128-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2024-01-18 | — | — | US | disclosed |
| US-20240018128-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2024-01-18 | — | — | US | disclosed |
| EP-3931194-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-12-06 | — | — | EP | disclosed |
| US-20230348496-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-11-02 | — | — | US | disclosed |
| US-20230348496-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-11-02 | — | — | US | disclosed |
| US-20230348496-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-11-02 | — | — | US | disclosed |
| EP-4208463-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | Syngenta Crop Protection AG (CH) | 2023-07-12 | — | — | EP | disclosed |
| EP-4204409-A2 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | Syngenta Crop Protection AG (CH) | 2023-07-05 | — | — | EP | disclosed |
| CN-116056577-A | Pesticidally active heterocyclic derivatives with sulfur containing substituents | 先正达农作物保护股份公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-116018344-A | Pesticidally active heterocyclic derivatives with sulfur containing substituents | 先正达农作物保护股份公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-115023426-A | Pesticidally active heterocyclic derivatives with sulfur-containing substituents | 先正达农作物保护股份公司 | 2022-09-06 | — | — | CN | disclosed |
| US-20220132850-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-05-05 | — | — | US | disclosed |
| US-20220132850-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-05-05 | — | — | US | disclosed |
| WO-2022049141-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-03-10 | — | — | WO | disclosed |
| WO-2022043576-A2 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-03-03 | — | — | WO | disclosed |
| EP-3931194-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | Syngenta Crop Protection AG (CH) | 2022-01-05 | — | — | EP | disclosed |
| CN-113811532-A | Pesticidally active heterocyclic derivatives with sulfur-containing substituents | 先正达农作物保护股份公司 | 2021-12-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12538924-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | CBR3, CBR1, CYCS | MRGPRX4 3385/4885EPHX2 1183/4885KDM4E 1249/4885 |
| US-20230348496-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | FOXM1, GLRX3, ACHE | MRGPRX4 1716/4885EPHX2 1326/4885KDM4E 2896/4885 |
| US-20240018128-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | FOXM1, GLRX3, ACHE | MRGPRX4 1716/4885EPHX2 1326/4885KDM4E 2896/4885 |
| US-20220132850-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, AADAC, ACHE | MRGPRX4 3554/4885EPHX2 1432/4885KDM4E 2168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.