Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153276 | 0.77 | FFAR1 (0.60) | NPC1RAB9ASMN1; SMN2CYP1A2HPGD | |
| SCHEMBL9150014 | 0.76 | FFAR1 (0.44) | NPC1RAB9ASMN1; SMN2CYP1A2HPGD | |
| SCHEMBL9155662 | 0.76 | MEN1 (0.47) | NPC1RAB9ASMN1; SMN2CYP1A2HPGD | |
| SCHEMBL9413683 | 0.70 | MEN1 (0.40) | NPC1RAB9ASMN1; SMN2CYP1A2HPGD | |
| SCHEMBL9153116 | 0.70 | SLC6A2 (0.42) | NPC1RAB9ASMN1; SMN2CYP1A2HPGD | |
| SCHEMBL17761209 | 0.69 | FFAR1 (0.50) | NPC1RAB9ASMN1; SMN2CYP2C19ALDH1A1 | |
| SCHEMBL12836119 | 0.69 | FFAR1 (0.50) | NPC1RAB9ASMN1; SMN2CYP2C19ALDH1A1 | |
| SCHEMBL8038720 | 0.68 | SLC6A2 (0.46) | NPC1RAB9ASMN1; SMN2CYP1A2HPGD | |
| SCHEMBL11250713 | 0.66 | ALDH1A1 (0.58) | NPC1RAB9ASMN1; SMN2CYP1A2HPGD | |
| SCHEMBL8497841 | 0.66 | MEN1 (0.46) | RAB9ASMN1; SMN2CYP1A2HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362765-A2 | PERFUME SYSTEMS | The Procter & Gamble Company (US) | 2011-09-07 | — | — | EP | claimed |
| WO-2010065446-A2 | PERFUME SYSTEMS | THE PROCTER & GAMBLE COMPANY (US) | 2010-06-10 | — | — | WO | claimed |