Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24397583 | 0.86 | CRBN (0.38) | CRBNKEAP1NFE2L2EPHX2TTR | |
| SCHEMBL24397611 | 0.85 | CRBN (0.36) | CRBNTTR | |
| SCHEMBL18886281 | 0.72 | CRBN (0.41) | CRBNTTR | |
| SCHEMBL17282361 | 0.72 | CRBN (0.41) | CRBNTTR | |
| SCHEMBL19164024 | 0.72 | CRBN (0.38) | CRBNTTR | |
| SCHEMBL24795789 | 0.71 | CRBN (0.38) | CRBNTTR | |
| SCHEMBL18886307 | 0.71 | CRBN (0.38) | CRBNTTR | |
| SCHEMBL13695971 | 0.71 | CRBN (0.38) | CRBNTTR | |
| SCHEMBL14922170 | 0.71 | CRBN (0.38) | CRBNTTR | |
| SCHEMBL23234313 | 0.71 | CRBN (0.38) | CRBNTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022094148-A1 | CONJUGATION REAGENTS AND METHODS USING 1,2-CYCLOHEXANEDIONES | Encodia, Inc. (US) | 2022-05-05 | — | — | WO | disclosed |