SCHEMBL23234313

SCHEMBL23234313

[N-]=[N+]=NCCOCCOCCNC(=O)CI

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 3/20 0.38
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ CA2 P00918 4/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ TTR P02766 1/20 0.33
▸ CA9 Q16790 3/20 0.31
▸ CA12 O43570 2/20 0.31
▸ CA1 P00915 2/20 0.31
▸ CA4 P22748 2/20 0.31
▸ CA14 Q9ULX7 2/20 0.31
▸ MGMT P16455 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14922170 1.00 CRBN (0.38) CRBNMEN1KMT2ACA2SMN1; SMN2
SCHEMBL30242774 1.00 CRBN (0.38) CRBNMEN1KMT2ACA2SMN1; SMN2
SCHEMBL18886281 0.88 CRBN (0.41) CRBNMEN1KMT2ACA2SMN1; SMN2
SCHEMBL17282361 0.88 CRBN (0.41) CRBNMEN1KMT2ACA2SMN1; SMN2
SCHEMBL19164024 0.88 CRBN (0.38) CRBNMEN1KMT2ACA2SMN1; SMN2
SCHEMBL14922169 0.87 CRBN (0.38) CRBNMEN1KMT2ACA2SMN1; SMN2
SCHEMBL31174135 0.87 CRBN (0.38) CRBNMEN1KMT2ACA2SMN1; SMN2
SCHEMBL24795789 0.87 CRBN (0.38) CRBNMEN1KMT2ACA2SMN1; SMN2
SCHEMBL18886307 0.87 CRBN (0.38) CRBNMEN1KMT2ACA2SMN1; SMN2
SCHEMBL13695971 0.87 CRBN (0.38) CRBNMEN1KMT2ACA2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240000964-A1 COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED BY USING THE SAME AJINOMOTO CO., INC. (JP) 2024-01-04 — — US disclosed
EP-4279502-A1 COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED THEREFROM AJINOMOTO CO., INC. (JP) 2023-11-22 — — EP disclosed
CN-116761819-A Compounds or salts thereof, and antibodies derived therefrom 味之素株式会社 2023-09-15 — — CN disclosed
US-20230248837-A1 Technology for Modulating Targeting Chimeras Induced by Cell-Penetrating Peptide and Application Thereof LIU, MIAO (CN) 2023-08-10 — — US disclosed
WO-2022154127-A1 COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED THEREFROM 味の素株式会社 2022-07-21 — — WO disclosed
US-20210139549-A1 COMPOUND HAVING AFFINITY SUBSTANCE TO ANTIBODY, CLEAVABLE PORTION, AND REACTIVE GROUP, OR SALT THEREOF AJINOMOTO CO., INC. (JP) 2021-05-13 — — US disclosed
EP-3808760-A1 COMPOUND COMPRISING SUBSTANCE HAVING AFFINITY FOR ANTIBODY, CLEAVAGE SITE AND REACTIVE GROUP, OR SALT THEREOF AJINOMOTO CO., INC. (JP) 2021-04-21 — — EP disclosed
CN-112262152-A Compound having affinity substance, cleavable moiety and reactive group for antibody, or salt thereof 味之素株式会社 2021-01-22 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240000964-A1 COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED BY USING THE SAME SSB, CTH, SCLY CRBN 340/4885MEN1 2419/4885KMT2A 991/4885
US-20210139549-A1 COMPOUND HAVING AFFINITY SUBSTANCE TO ANTIBODY, CLEAVABLE PORTION, AND REACTIVE GROUP, OR SALT THEREOF FCGR3B, FCGR2A, FCGR1A CRBN 676/4885MEN1 1262/4885KMT2A 922/4885
US-20230248837-A1 Technology for Modulating Targeting Chimeras Induced by Cell-Penetrating Peptide and Application Thereof VIP, GHITM, MYCBP CRBN 226/4885MEN1 1339/4885KMT2A 3720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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