SCHEMBL24795789

SCHEMBL24795789

[N-]=[N+]=NCCOCCOCCOCCNC(=O)CBr

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 3/20 0.38
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ TTR P02766 1/20 0.33
▸ CA2 P00918 4/20 0.31
▸ CA9 Q16790 3/20 0.31
▸ CA12 O43570 2/20 0.31
▸ CA1 P00915 2/20 0.31
▸ CA4 P22748 2/20 0.31
▸ CA14 Q9ULX7 2/20 0.31
▸ MGMT P16455 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13695971 1.00 CRBN (0.38) CRBNMEN1KMT2ASMN1; SMN2TTR
SCHEMBL31174135 1.00 CRBN (0.38) CRBNMEN1KMT2ASMN1; SMN2TTR
SCHEMBL14922169 1.00 CRBN (0.38) CRBNMEN1KMT2ASMN1; SMN2TTR
SCHEMBL29787158 1.00 CRBN (0.38) CRBNMEN1KMT2ASMN1; SMN2TTR
SCHEMBL18886281 0.88 CRBN (0.41) CRBNMEN1KMT2ASMN1; SMN2TTR
SCHEMBL17282361 0.88 CRBN (0.41) CRBNMEN1KMT2ASMN1; SMN2TTR
SCHEMBL19164024 0.88 CRBN (0.38) CRBNMEN1KMT2ASMN1; SMN2TTR
SCHEMBL14922170 0.87 CRBN (0.38) CRBNMEN1KMT2ASMN1; SMN2TTR
SCHEMBL23234313 0.87 CRBN (0.38) CRBNMEN1KMT2ASMN1; SMN2TTR
SCHEMBL18886307 0.87 CRBN (0.38) CRBNMEN1KMT2ASMN1; SMN2TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4281775-B1 SYSTEMS AND METHODS FOR BIOMOLECULE PREPARATION NAUTILUS SUBSIDIARY INC (US) 2026-04-29 — — EP disclosed
EP-4281775-A1 SYSTEMS AND METHODS FOR BIOMOLECULE PREPARATION Nautilus Subsidiary, Inc. (US) 2023-11-29 — — EP disclosed
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. 2023-08-10 — — US disclosed
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. 2023-08-10 — — US disclosed
US-20230212322-A1 SYSTEMS AND METHODS FOR BIOMOLECULE PREPARATION NAUTILUS SUBSIDIARY, INC. 2023-07-06 — — US disclosed
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 — — US disclosed
WO-2022264114-A2 ROS SENSITIVE DIAZABORINES FOR THE CONSTRUCTION OF STIMULI-RESPONSIVE BIOCONJUGATES TECHNOPHAGE, INVESTIGAÇÃO E DESENVOLVIMENTO EM BIOTECHNOLOGIA, S.A. (PT) 2022-12-22 — — WO disclosed
WO-2022264114-A2 ROS SENSITIVE DIAZABORINES FOR THE CONSTRUCTION OF STIMULI-RESPONSIVE BIOCONJUGATES TECHNOPHAGE, INVESTIGAÇÃO E DESENVOLVIMENTO EM BIOTECHNOLOGIA, S.A. (PT) 2022-12-22 — — WO disclosed
EP-4087584-A2 CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES Lycia Therapeutics, Inc. (US) 2022-11-16 — — EP disclosed
WO-2022159663-A1 SYSTEMS AND METHODS FOR BIOMOLECULE PREPARATION NAUTILUS BIOTECHNOLOGY, INC. (US) 2022-07-28 — — WO disclosed
US-20220227890-A1 SYSTEMS AND METHODS FOR BIOMOLECULE PREPARATION NAUTILUS SUBSIDIARY, INC. 2022-07-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates M6PR, ASGR1, IGF2R CRBN 3454/4885MEN1 1529/4885KMT2A 2580/4885
US-20220227890-A1 SYSTEMS AND METHODS FOR BIOMOLECULE PREPARATION PSAP, NPEPPS, VIP CRBN 1306/4885MEN1 986/4885KMT2A 4850/4885
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES ASGR1, LAMP2, FCGR2A CRBN 2889/4885MEN1 4092/4885KMT2A 3976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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