Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.48 |
| ▸ | CECR2 | Q9BXF3 | 4/20 | 0.48 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.48 |
| ▸ | TAF1 | P21675 | 1/20 | 0.48 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.48 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.48 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.48 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.48 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.48 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24397849 | 0.90 | BRD4 (0.46) | BRD4CECR2BRD9TRIM24TAF1 | |
| SCHEMBL24397954 | 0.86 | BRD4 (0.46) | BRD4CECR2BRD9TRIM24TAF1 | |
| SCHEMBL24397906 | 0.86 | BRD4 (0.49) | BRD4 | |
| SCHEMBL24397982 | 0.85 | BRD4 (0.52) | BRD4CECR2BRD9TRIM24TAF1 | |
| SCHEMBL24398005 | 0.83 | BRD9 (0.47) | BRD4CECR2BRD9TRIM24TAF1 | |
| SCHEMBL24398044 | 0.83 | BRD4 (0.55) | BRD4CECR2BRD9TRIM24TAF1 | |
| SCHEMBL24397887 | 0.83 | CECR2 (0.48) | BRD4CECR2BRD9TAF1 | |
| SCHEMBL24398081 | 0.82 | BRD4 (0.46) | BRD4 | |
| SCHEMBL24397990 | 0.82 | BRD4 (0.46) | BRD4BRD2 | |
| SCHEMBL24398000 | 0.81 | BRD4 (0.46) | BRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022090699-A1 | PYRIDONE-CONTAINING COMPOUNDS AS BROMODOMAIN PROTEIN INHIBITORS | In4Derm Limited (GB) | 2022-05-05 | — | — | WO | disclosed |
| WO-2022090699-A1 | PYRIDONE-CONTAINING COMPOUNDS AS BROMODOMAIN PROTEIN INHIBITORS | In4Derm Limited (GB) | 2022-05-05 | — | — | WO | disclosed |