SCHEMBL24399

SCHEMBL24399

COC1CCc2cc(C(Cl)=NO)ccc21

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24398 1.00 IDO1 (0.31) IDO1L3MBTL1
SCHEMBL23884 0.72 ALDH1A1 (0.36) IDO1L3MBTL1
SCHEMBL23883 0.72 ALDH1A1 (0.36) IDO1L3MBTL1
SCHEMBL33088 0.71 CA12 (0.43) L3MBTL1
SCHEMBL29208081 0.71 CA12 (0.41)
SCHEMBL21178574 0.71 BDKRB1 (0.40) L3MBTL1
SCHEMBL22547324 0.70 SRD5A1 (0.46) IDO1
SCHEMBL25694 0.70 SLC6A4 (0.47) IDO1
SCHEMBL8203404 0.70 ALDH1A1 (0.50) L3MBTL1
SCHEMBL28470161 0.67 FFAR1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012026403-A1 CONDENSED RING COMPOUND 日本曹達株式会社 (JP) 2012-03-01 WO disclosed