Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29208081 | 0.81 | CA12 (0.41) | CA12CA7CA14TAS1R3TAS1R1 | |
| SCHEMBL25651 | 0.80 | CA12 (0.47) | CA12CA7CA14TAS1R3TAS1R1 | |
| SCHEMBL21178574 | 0.78 | BDKRB1 (0.40) | CA12CA7CA14TAS1R3TAS1R1 | |
| SCHEMBL26295 | 0.78 | CA12 (0.46) | CA12CA7CA14TAS1R3TAS1R1 | |
| SCHEMBL2554893 | 0.74 | PKM (0.47) | CA12CA7CA14TAS1R3TAS1R1 | |
| SCHEMBL14890213 | 0.72 | CA12 (0.55) | CA12CA7CA14DHODHSMN1; SMN2 | |
| SCHEMBL24398 | 0.71 | IDO1 (0.31) | L3MBTL1 | |
| SCHEMBL24399 | 0.71 | IDO1 (0.31) | L3MBTL1 | |
| SCHEMBL803498 | 0.70 | KMT2A (0.47) | CA12CA7CA14TAS1R3TAS1R1 | |
| SCHEMBL24120 | 0.69 | CA12 (0.48) | CA12CA7CA14PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026403-A1 | CONDENSED RING COMPOUND | 日本曹達株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |