Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.39 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.39 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14048468 | 0.87 | ELANE (0.59) | ELANECFDLMNACYP3A4ESR1 | |
| SCHEMBL10005890 | 0.82 | ESR1 (0.61) | SLC7A5KEAP1LMNACYP3A4ESR1 | |
| SCHEMBL16592194 | 0.82 | ESR1 (0.61) | SLC7A5KEAP1LMNACYP3A4ESR1 | |
| SCHEMBL8349574 | 0.82 | ESR1 (0.61) | SLC7A5KEAP1LMNACYP3A4ESR1 | |
| SCHEMBL777803 | 0.80 | ELANE (0.62) | ELANECFDLMNACYP3A4ESR1 | |
| SCHEMBL14708691 | 0.79 | ESR1 (0.61) | SLC7A5KEAP1LMNACYP3A4ESR1 | |
| SCHEMBL25518105 | 0.78 | KEAP1 (0.52) | SLC7A5KEAP1CYP3A4ESR1ESR2 | |
| 4-Acetoxyphenol SCHEMBL203149 | 0.77 | LMNA (0.67) | ELANELMNACYP3A4ESR1ESR2 | |
| SCHEMBL8357015 | 0.76 | ESR1 (0.69) | SLC7A5KEAP1CYP3A4ESR1ESR2 | |
| SCHEMBL2688206 | 0.76 | KMT2A (0.70) | ELANELMNAESR1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220135731-A1 | MODIFIED ARYLHYDROXY COMPOUNDS FOR THE PRODUCTION OF POLYURETHANE OR POLYISOCYANURATE | Hexion GmbH (DE) | 2022-05-05 | — | — | US | disclosed |