SCHEMBL8349574

SCHEMBL8349574

Oc1ccc(Cc2ccc(O)c(Cc3ccc(O)cc3)c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.61
ESR2 Q92731 2/20 0.61
KEAP1 Q14145 1/20 0.61
MAPT P10636 3/20 0.55
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA4 P22748 1/20 0.54
CA6 P23280 1/20 0.54
IDH1 O75874 1/20 0.50
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
ALOX15 P16050 3/20 0.48
CYP3A4 P08684 2/20 0.48
HPGD P15428 2/20 0.48
HIF1A Q16665 2/20 0.48
HSD17B10 Q99714 1/20 0.48
ALOX5 P09917 2/20 0.47
SLC7A5 Q01650 1/20 0.46
SNCA P37840 1/20 0.46
IGF1R P08069 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10005890 1.00 ESR1 (0.61) ESR1ESR2KEAP1MAPTCA1
SCHEMBL16592194 1.00 ESR1 (0.61) ESR1ESR2KEAP1MAPTCA1
SCHEMBL14708691 0.96 ESR1 (0.61) ESR1ESR2KEAP1MAPTCA1
SCHEMBL8357015 0.89 ESR1 (0.69) ESR1ESR2KEAP1MAPTCA1
SCHEMBL11683563 0.88 ESR1 (0.56) ESR1ESR2KEAP1MAPTCA1
SCHEMBL8430733 0.86 KEAP1 (0.59) ESR1ESR2KEAP1MAPTCA1
SCHEMBL8680249 0.86 ESR1 (0.55) ESR1ESR2KEAP1MAPTCA1
SCHEMBL10886054 0.85 IDH1 (0.70) KEAP1MAPTCA1CA2CA4
SCHEMBL13609034 0.85 KEAP1 (0.59) ESR1ESR2KEAP1MAPTMEN1
SCHEMBL9173452 0.85 IDH1 (0.70) KEAP1MAPTCA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116102407-B Method for preparing gastrodia elata extract 2, 4-bis (4-hydroxybenzyl) phenol 北京化工大学 2024-07-23 CN claimed
CN-116102407-A Method for preparing gastrodia elata extract 2, 4-bis (4-hydroxybenzyl) phenol 北京化工大学 2023-05-12 CN claimed
CN-116102407-B Method for preparing gastrodia elata extract 2, 4-bis (4-hydroxybenzyl) phenol 北京化工大学 2024-07-23 CN disclosed
CN-116102407-B Method for preparing gastrodia elata extract 2, 4-bis (4-hydroxybenzyl) phenol 北京化工大学 2024-07-23 CN disclosed
CN-116102407-B Method for preparing gastrodia elata extract 2, 4-bis (4-hydroxybenzyl) phenol 北京化工大学 2024-07-23 CN disclosed
CN-116768756-A Novel 2-hydroxy diaryl methane compound and efficient synthesis method thereof 湖南大学 2023-09-19 CN disclosed
CN-116102407-A Method for preparing gastrodia elata extract 2, 4-bis (4-hydroxybenzyl) phenol 北京化工大学 2023-05-12 CN disclosed
CN-116102407-A Method for preparing gastrodia elata extract 2, 4-bis (4-hydroxybenzyl) phenol 北京化工大学 2023-05-12 CN disclosed
CN-116102407-A Method for preparing gastrodia elata extract 2, 4-bis (4-hydroxybenzyl) phenol 北京化工大学 2023-05-12 CN disclosed
US-20220135731-A1 MODIFIED ARYLHYDROXY COMPOUNDS FOR THE PRODUCTION OF POLYURETHANE OR POLYISOCYANURATE Hexion GmbH (DE) 2022-05-05 US disclosed
US-20180201825-A1 COATING FOR CAPTURING SULFIDES DOW GLOBAL TECHNOLOGIES LLC (US) 2018-07-19 US disclosed
US-20180179438-A1 COATING FOR CONTROLLED RELEASE DOW GLOBAL TECHNOLOGIES LLC (US) 2018-06-28 US disclosed
WO-2017003819-A1 COATING FOR CAPTURING SULFIDES DOW GLOBAL TECHNOLOGIES LLC (US) 2017-01-05 WO disclosed
US-5948587-A MIXTURE OF ALKALI-SOLUBLE NOVOLAK, 1,2-NAPHTHOQUINONEDIAZIDESULFONIC ESTER AND PHENOLIC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-09-07 US disclosed
US-5853949-A Method of synthesizing polyphenol compound and positive working photoresist composition comprising polyphenol compound FUJI PHOTO FILM CO., LTD. (JP) 1998-12-29 US disclosed
US-5683851-A THYMOL OR ISOTHYMOL PHENOLIC RESIN, NAPHTHOQUINONEDIAZIDESULFONATE, LOW MOLECULAR WEIGHT PHENOLIC POLYHYDROXIDE FUJI PHOTO FILM CO., LTD. (JP) 1997-11-04 US disclosed