Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Benzyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.82 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Alcohol SCHEMBL4345690 | 1.00 | TSHR (0.82) | TSHRCES2CES1AKR1B1LTA4H | |
| Benzyl Alcohol SCHEMBL8755065 | 0.97 | TSHR (0.78) | TSHRCES2CES1AKR1B1LTA4H | |
| Benzyl Alcohol SCHEMBL8755073 | 0.97 | TSHR (0.78) | TSHRCES2CES1AKR1B1LTA4H | |
| Benzyl Alcohol SCHEMBL27504130 | 0.97 | TSHR (0.78) | TSHRCES2CES1AKR1B1LTA4H | |
| Benzyl Alcohol SCHEMBL27698756 | 0.97 | TSHR (0.78) | TSHRCES2CES1AKR1B1LTA4H | |
| Benzyl Alcohol SCHEMBL11353823 | 0.91 | TSHR (1.00) | TSHRCES2CES1AKR1B1LTA4H | |
| Benzyl Alcohol SCHEMBL147 | 0.91 | — | — | |
| Benzyl Alcohol SCHEMBL433990 | 0.91 | TSHR (1.00) | TSHRCES2CES1AKR1B1LTA4H | |
| Benzyl Alcohol SCHEMBL27787318 | 0.91 | TSHR (1.00) | TSHRCES2CES1AKR1B1LTA4H | |
| Benzyl Alcohol SCHEMBL27703677 | 0.91 | TSHR (1.00) | TSHRCES2CES1AKR1B1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010168-A1 | Unique Dual-Action Therapeutics | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-12 | — | — | US | claimed |
| WO-2010051044-A1 | UNIQUE DUAL-ACTION THERAPEUTICS | UNIVERSITY OF MEDICINE AND DENTISTRY (US) | 2010-05-06 | — | — | WO | claimed |
| CN-104735986-B | Liquid agrochemical composition including polymeric viscosifier and containing alcohol solvent system and with the liquid weeding composition containing alcohol solvent system | 先正达参股股份有限公司 | 2018-08-31 | — | — | CN | disclosed |
| EP-2588454-A1 | SUBSTITUTED DICYANOPYRIDINES AND USE THEREOF | Bayer Intellectual Property GmbH (DE) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012000945-A1 | SUBSTITUTED DICYANOPYRIDINES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-05 | — | — | WO | disclosed |
| WO-2010128095-A1 | ECTOPARASITICIDAL COMPOSITIONS | NOVARTIS AG (CH) | 2010-11-11 | — | — | WO | disclosed |
| US-20080207670-A1 | Dermally Applicable Formulations For Treating Skin Diseases in Animals | BAYER HEALTHCARE AG (DE) | 2008-08-28 | — | — | US | disclosed |
| EP-1791522-A1 | DERMALLY APPLICABLE FORMULATIONS FOR TREATING SKIN DISEASES IN ANIMALS | Bayer HealthCare AG (DE) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006029726-A1 | DERMALLY APPLICABLE FORMULATIONS FOR TREATING SKIN DISEASES IN ANIMALS | BAYER HEALTHCARE AG (DE) | 2006-03-23 | — | — | WO | disclosed |
| US-6548464-B1 | Applying a formulation containing from 92 to 99% by weight of an alkylene carbonate (propylene carbonate) and 1-8% by weight of an alcohol (benzyl alcohol) for removing paint coating from the surface of aluminum metal | HUNTSMAN PETROCHEMICAL CORPORATION | 2003-04-15 | — | — | US | disclosed |
| US-4963591-A | CELLULOSE ETHER IN LOWER ALIPHATIC ALCOHOL SOLVENT | CARTER-WALLACE INC. (US) | 1990-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010168-A1 | Unique Dual-Action Therapeutics | ACHE, PDE1A, PDE1C | TSHR 3194/4885CES2 32/4885CES1 13/4885 |
| US-20080207670-A1 | Dermally Applicable Formulations For Treating Skin Diseases in Animals | KRT18, CUTA, PIGS | TSHR 4586/4885CES2 856/4885CES1 1902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.