SCHEMBL24400331

SCHEMBL24400331

Cn1c(=O)ccn(Cl)c1=O

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BRPF1 P55201 2/20 0.34
CA12 O43570 1/20 0.34
BRD4 O60885 1/20 0.34
CA9 Q16790 1/20 0.34
KAT2B Q92831 1/20 0.34
BRD9 Q9H8M2 1/20 0.34
HSD17B13 Q7Z5P4 5/20 0.33
CYP3A4 P08684 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
CRBN Q96SW2 1/20 0.32
PIK3CD O00329 1/20 0.31
PIK3CA P42336 1/20 0.31
PIK3CB P42338 1/20 0.31
PIK3CG P48736 1/20 0.31
ALDH1A1 P00352 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
HPGD P15428 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24400292 0.77 LPO (0.33) BRPF1CA12BRD4CA9KAT2B
SCHEMBL100263 0.75 CRBN (0.44) BRPF1CA12BRD4CA9KAT2B
Water SCHEMBL6505685 0.73 CRBN (0.43) BRPF1CA12BRD4CA9KAT2B
Hydrochloric Acid SCHEMBL7524493 0.73 CRBN (0.43) BRPF1CA12BRD4CA9KAT2B
SCHEMBL28318560 0.71 BRPF1 (0.34) BRPF1CA12BRD4CA9KAT2B
SCHEMBL6666695 0.71
SCHEMBL7899234 0.71 CRBN (0.41) BRPF1CA12BRD4CA9KAT2B
SCHEMBL13947776 0.71 HSD17B13 (0.43) HSD17B13
SCHEMBL28143522 0.71 HSD17B13 (0.31) BRPF1CA12BRD4CA9KAT2B
SCHEMBL11217234 0.68 HSD17B13 (0.35) BRPF1CA12BRD4CA9KAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110156750-A Pyrimidine ring14The preparation method of the amber love song Ge Lieting of C flag 无锡贝塔医药科技有限公司 2019-08-23 CN claimed
CN-109734673-A A kind of purification process of compound 浙江华贝药业有限责任公司 2019-05-10 CN claimed
CN-106336396-B A kind of preparation method of alogliptin benzoate 合肥立方制药股份有限公司 2019-04-09 CN claimed
CN-109020900-A The preparation method of the chloro- 3- methyluracil of 6- 浙江先锋科技股份有限公司 2018-12-18 CN claimed
CN-108822080-A The preparation method of amber love song Ge Lieting 四川新斯顿制药股份有限公司 2018-11-16 CN claimed
CN-108586360-A A kind of preparation method of the chloro- 3- methyluracils of 6- 峨眉山宏昇药业股份有限公司 2018-09-28 CN claimed
CN-105541793-B The synthetic method of bent Ge Lieting 河北国龙制药有限公司 2018-08-10 CN claimed
CN-207435359-U A kind of chloro- 3- methyluracils process units of 6- 杭州布朗生物医药科技有限公司 2018-06-01 CN claimed
CN-107540656-A A kind of preparation method of SYR-322 常州市第四制药厂有限公司 2018-01-05 CN claimed
CN-106632241-A Preparation method of trelagliptin succinate 安徽省金楠医疗科技有限公司 2017-05-10 CN claimed
CN-106279104-A A kind of process modification method preparing succinum love song Ge Lieting 杭州新博思生物医药有限公司 2017-01-04 CN claimed
CN-105646447-A Synthesis method of dipeptidyl peptidase inhibitor 北京康立生医药技术开发有限公司 2016-06-08 CN claimed
US-20230399423-A1 POLYMERIC DISINFECTANTS AND USES THEREOF TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2023-12-14 US disclosed
CN-111693627-B Detection method and application of 6-chloro-3-methyl uracil and related substances thereof 山西振东制药股份有限公司 2022-05-13 CN disclosed
WO-2022091091-A1 POLYMERIC DISINFECTANTS AND USES THEREOF TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) 2022-05-05 WO disclosed
CN-111693627-A Detection method and application of 6-chloro-3-methyl uracil and related substances thereof 山西振东制药股份有限公司 2020-09-22 CN disclosed
CN-104086527-B A kind of synthetic method of SYR-322 湖南欧亚生物有限公司 2016-09-21 CN disclosed
CN-104193726-B A kind of synthetic method of SYR-322 江苏德源药业股份有限公司 2016-08-24 CN disclosed
CN-105658222-A Free base crystals 细胞内治疗公司 2016-06-08 CN disclosed
CN-105646447-A Synthesis method of dipeptidyl peptidase inhibitor 北京康立生医药技术开发有限公司 2016-06-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399423-A1 POLYMERIC DISINFECTANTS AND USES THEREOF CUTA, PRKDC, PIK3C3 BRPF1 1821/4885CA12 2375/4885BRD4 2335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.