Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2A1 | Q16548 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RNF4 | P78317 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24401088 | 0.79 | SCN9A (0.40) | BCL2A1RNF4DRD2DRD3MEN1 | |
| SCHEMBL14809010 | 0.79 | BCL2A1 (0.48) | BCL2A1TP53RNF4MAPTTSPO | |
| SCHEMBL14809012 | 0.79 | BCL2A1 (0.48) | BCL2A1TP53RNF4MAPTTSPO | |
| SCHEMBL20552582 | 0.76 | STK17B (0.38) | ALDH1A1LMNAKMT2A | |
| SCHEMBL3065683 | 0.75 | BCL2A1 (0.42) | BCL2A1ALDH1A1 | |
| SCHEMBL23251854 | 0.75 | HTR2C (0.42) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL21262061 | 0.75 | BCL2A1 (0.43) | BCL2A1SMN1; SMN2TP53GAAMAPT | |
| SCHEMBL19513028 | 0.75 | AGXT (0.40) | SMN1; SMN2TP53MAPTDRD3CHRM2 | |
| SCHEMBL3660817 | 0.74 | KEAP1 (0.49) | BCL2A1RNF4TRPM8 | |
| SCHEMBL4002016 | 0.74 | MLYCD (0.43) | BCL2A1SMN1; SMN2TP53MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4238974-A1 | HIGH-ACTIVITY WNT PATHWAY INHIBITOR COMPOUND | Adlai Nortye Biopharma Co., Ltd. (CN) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022089454-A1 | HIGH-ACTIVITY WNT PATHWAY INHIBITOR COMPOUND | 杭州阿诺生物医药科技有限公司 | 2022-05-05 | — | — | WO | disclosed |