Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | RNF4 | P78317 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24401097 | 0.79 | BCL2A1 (0.46) | RNF4MEN1KMT2ADRD2DRD3 | |
| SCHEMBL2113412 | 0.72 | KCNH2 (0.37) | SCN9AHDAC1HDAC8HDAC6MRGPRX4 | |
| SCHEMBL14809012 | 0.71 | BCL2A1 (0.48) | RNF4MEN1KMT2ABCL2A1 | |
| SCHEMBL14809010 | 0.71 | BCL2A1 (0.48) | RNF4MEN1KMT2ABCL2A1 | |
| SCHEMBL2599941 | 0.69 | NR1H4 (0.37) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL3225600 | 0.68 | L3MBTL1 (0.39) | RNF4HDAC6MEN1KMT2AMLYCD | |
| SCHEMBL2110880 | 0.68 | KCNH2 (0.39) | HDAC1HDAC8HDAC6MRGPRX4 | |
| SCHEMBL1888092 | 0.68 | MLYCD (0.40) | MLYCDBCL2A1 | |
| SCHEMBL24401094 | 0.68 | LOXL2 (0.41) | SCN9ASCN10AMRGPRX4PLAAT3PLAAT5 | |
| SCHEMBL19513028 | 0.68 | AGXT (0.40) | MEN1KMT2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4238974-A1 | HIGH-ACTIVITY WNT PATHWAY INHIBITOR COMPOUND | Adlai Nortye Biopharma Co., Ltd. (CN) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022089454-A1 | HIGH-ACTIVITY WNT PATHWAY INHIBITOR COMPOUND | 杭州阿诺生物医药科技有限公司 | 2022-05-05 | — | — | WO | disclosed |