Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 3/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25911631 | 0.82 | LOXL2 (0.46) | GRIN1GRIN2BPSD | |
| SCHEMBL25269987 | 0.79 | GRIN1 (0.40) | GRIN1GRIN2BDAOPPARDTRPV4 | |
| SCHEMBL21503682 | 0.78 | LOXL2 (0.40) | GRIN1GRIN2BDAOPPARDTRPV4 | |
| SCHEMBL30755398 | 0.77 | LMNA (0.58) | LMNAMAPTPSDHDAC2 | |
| SCHEMBL26202009 | 0.77 | CYP3A4 (0.40) | GRIN1GRIN2BDAOPPARDTRPV4 | |
| Hydrochloric Acid SCHEMBL21491894 | 0.77 | LMNA (0.41) | GRIN1GRIN2BDAOPPARDTRPV4 | |
| Hydrochloric Acid SCHEMBL30744436 | 0.77 | LMNA (0.41) | GRIN1GRIN2BDAOPPARDTRPV4 | |
| SCHEMBL21493002 | 0.76 | PPARD (0.42) | PPARDLMNAMAPTPREP | |
| SCHEMBL30744539 | 0.76 | PPARD (0.42) | PPARDLMNAMAPTPREP | |
| SCHEMBL8209503 | 0.76 | KLKB1 (0.45) | PPARDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4238974-A1 | HIGH-ACTIVITY WNT PATHWAY INHIBITOR COMPOUND | Adlai Nortye Biopharma Co., Ltd. (CN) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022089454-A1 | HIGH-ACTIVITY WNT PATHWAY INHIBITOR COMPOUND | 杭州阿诺生物医药科技有限公司 | 2022-05-05 | — | — | WO | disclosed |