SCHEMBL24407693

SCHEMBL24407693

O=C(O)c1ccc(Oc2c(I)cc(I)cc2I)cc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 8/20 0.50
PCNA P12004 7/20 0.50
THRA P10827 6/20 0.50
LMNA P02545 3/20 0.50
POLB P06746 2/20 0.50
HIF1A Q16665 2/20 0.50
ABCB11 O95342 2/20 0.50
GABRA1 P14867 2/20 0.50
PPARG P37231 2/20 0.50
GABRA2 P47869 2/20 0.50
GABRB2 P47870 2/20 0.50
CYP1A2 P05177 1/20 0.50
PGR P06401 1/20 0.50
CHRM2 P08172 1/20 0.50
HTR1A P08908 1/20 0.50
ADRA2A P08913 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
AR P10275 1/20 0.50
CYP2C9 P11712 1/20 0.50
HPGD P15428 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24407812 0.90 THRB (0.47) THRBPCNATHRALMNAPOLB
SCHEMBL24407806 0.82 ALDH1A1 (0.53) POLBHPGDRXRATSHRALDH1A1
SCHEMBL14213143 0.81 ALDH1A1 (0.65) LMNAPOLBCYP1A2PGRCYP2C9
SCHEMBL24407715 0.81 THRB (0.52) THRBPCNATHRALMNAPOLB
SCHEMBL24407858 0.79 ALDH1A1 (0.50) THRBPCNATHRALMNAPOLB
SCHEMBL25894140 0.79 HPGD (0.44) HPGDTSHRALDH1A1CA12CA1
SCHEMBL24407680 0.79 XDH (0.43) THRBPCNATHRALMNAPOLB
SCHEMBL25894780 0.78 TPMT (0.43) LMNAHIF1ACYP1A2PGRADORA3
SCHEMBL24407691 0.78 ALDH1A1 (0.49) LMNAPOLBCYP1A2PGRHPGD
SCHEMBL24407685 0.78 ALDH1A1 (0.45) THRBPCNATHRALMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220146935-A1 CARBOXYLATE, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-05-12 US disclosed