SCHEMBL24409018

SCHEMBL24409018

Cc1ccccc1-c1cc(OCC(=O)O)nn1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.51
FABP3 P05413 2/20 0.47
HTT P42858 1/20 0.43
FFAR1 O14842 4/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
FABP4 P15090 3/20 0.40
FABP5 Q01469 1/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4E B2RXH2 1/20 0.39
PPARG P37231 2/20 0.39
PPARA Q07869 2/20 0.39
ADORA2B P29275 1/20 0.38
ADORA1 P30542 1/20 0.38
PPARD Q03181 1/20 0.38
ALOX15 P16050 1/20 0.38
S1PR1 P21453 1/20 0.38
S1PR3 Q99500 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24409322 0.87 MMP1 (0.47) PKMFABP3ALDH1A1MEN1KMT2A
SCHEMBL24425000 0.86 ALDH1A1 (0.47) HTTALDH1A1KDM4E
SCHEMBL24425100 0.86 PKM (0.50) PKMFABP3HTTALDH1A1TSHR
SCHEMBL24409015 0.86 PKM (0.53) PKMFABP3HTTFFAR1ALDH1A1
SCHEMBL24408997 0.86 PKM (0.50) PKMFABP3HTTFABP4FABP5
SCHEMBL24409308 0.83 PKM (0.56) PKMFABP3HTTALDH1A1TSHR
SCHEMBL24425297 0.80 PKM (0.55) PKMHTTALDH1A1TSHRFABP4
SCHEMBL27114051 0.79 PKM (0.51) PKMHTTALDH1A1TSHRMEN1
SCHEMBL27114063 0.78 PKM (0.53) PKMFABP3HTTALDH1A1TSHR
SCHEMBL24409116 0.78 PKM (0.50) PKMHTTFFAR1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022096450-A1 USE OF [(1,5-DIPHENYL-1H-PYRAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AND THEIR SALTS AND COMPOSITIONS CONTAINING THEM, FOR REDUCING PHYTOTOXIC EFFECTS OF AGROCHEMICALS, IN PARTICULAR OF HERBICIDES, IN USEFUL PLANTS AND CROP PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2022-05-12 WO disclosed