SCHEMBL24409173

SCHEMBL24409173

c1ccc([SiH](c2ccccc2)c2ccc(-c3ccc([SiH](c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
TAAR1 Q96RJ0 3/20 0.41
CYP1A2 P05177 2/20 0.41
MAPK1 P28482 1/20 0.41
CYP3A4 P08684 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MMP3 P08254 1/20 0.41
BCL2L1 Q07817 1/20 0.41
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
MGLL Q99685 1/20 0.36
KIF11 P52732 1/20 0.36
NOTUM Q6P988 1/20 0.35
ALOX5 P09917 1/20 0.35
CYP1A1 P04798 1/20 0.33
CYP1B1 Q16678 1/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28753733 0.97 ALDH1A1 (0.53) ALDH1A1TAAR1CYP1A2MAPK1CYP3A4
SCHEMBL15987409 0.94 ALDH1A1 (0.56) ALDH1A1TAAR1CYP1A2MAPK1CYP3A4
Biphenyl SCHEMBL27949639 0.90 ALDH1A1 (0.60) ALDH1A1TAAR1CYP1A2MAPK1CYP3A4
SCHEMBL703965 0.90 ALDH1A1 (0.38) ALDH1A1MAPK1CYP3A4HSD17B10TDP1
SCHEMBL17463831 0.87 CYP3A4 (0.64) ALDH1A1TAAR1CYP1A2CYP3A4HSD17B10
Benzene SCHEMBL27873242 0.87 ALDH1A1 (0.40) ALDH1A1MAPK1CYP3A4HSD17B10TDP1
SCHEMBL38902 0.87 ALDH1A1 (0.40) ALDH1A1MAPK1CYP3A4HSD17B10TDP1
SCHEMBL22428744 0.83 ALDH1A1 (0.39) ALDH1A1TAAR1CYP1A2MAPK1CYP3A4
SCHEMBL11256956 0.83 ALDH1A1 (0.38) ALDH1A1MAPK1CYP3A4HSD17B10TDP1
SCHEMBL38651919 0.83 ALDH1A1 (0.38) ALDH1A1MAPK1CYP3A4HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220146931-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220146931-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN RER1, FGFR1, CLIC1 ALDH1A1 723/4885TAAR1 730/4885CYP1A2 451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.