Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24409690 | 0.88 | SMN1; SMN2 (0.40) | MAPTGAASMN1; SMN2ALDH1A1TLR8 | |
| SCHEMBL19968181 | 0.84 | TLR7 (0.44) | TLR8TLR7 | |
| SCHEMBL24409692 | 0.84 | CYP1A2 (0.38) | MAPTGAASMN1; SMN2ALDH1A1TLR8 | |
| SCHEMBL310769 | 0.79 | CYP3A4 (0.41) | MAPTALDH1A1MEN1KMT2AACSS2 | |
| SCHEMBL1486523 | 0.75 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL3867677 | 0.74 | BRD4 (0.43) | MAPTGAAMEN1KMT2ATLR7 | |
| SCHEMBL27640403 | 0.73 | CYP3A4 (0.39) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL24409691 | 0.73 | TLR7 (0.51) | TLR8TLR7 | |
| SCHEMBL1486736 | 0.72 | BRD4 (0.40) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1486493 | 0.72 | CYP3A4 (0.43) | MAPTALDH1A1MEN1KDRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144833-A1 | IMIDAZOQUINOLINE DERIVATIVES AND THEIR USE IN THERAPY | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144833-A1 | IMIDAZOQUINOLINE DERIVATIVES AND THEIR USE IN THERAPY | MAVS, IRF3, MYD88 | MAPT 2548/4885GAA 3957/4885SMN1; SMN2 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.