Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 2/20 | 0.34 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 8/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22541779 | 0.88 | ARG1 (0.40) | ARG1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL19738913 | 0.81 | KMT2A (0.39) | ARG1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL25738639 | 0.81 | ARG1 (0.38) | ARG1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL17815919 | 0.78 | ARG1 (0.43) | ARG1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL25036349 | 0.78 | ARG1 (0.37) | ARG1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL24381885 | 0.76 | LMNA (0.37) | DPP4DPP8DPP9 | |
| SCHEMBL24322589 | 0.76 | ALDH1A1 (0.49) | — | |
| SCHEMBL19735104 | 0.76 | ARG1 (0.36) | ARG1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL9979887 | 0.76 | — | — | |
| SCHEMBL12765231 | 0.73 | KDM1A (0.50) | ARG1DPP4DPP8DPP9HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022096361-A1 | IMIDAZO[4,5-C]QUINOLINE COMPOUNDS AND THEIR USE AS ATM KINASE INHIBITORS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2022-05-12 | — | — | WO | disclosed |