Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2441173 | 0.81 | GPR17 (0.38) | POLBTSHRLMNAHPGDALDH1A1 | |
| SCHEMBL2441467 | 0.80 | NOTUM (0.48) | HPGDALDH1A1MEN1KMT2AALOX12 | |
| SCHEMBL9651251 | 0.79 | IAPP (0.37) | TSHRLMNAALDH1A1TGM2GPR52 | |
| SCHEMBL2059392 | 0.76 | EGFR (0.55) | EGFRFFAR1NPC1RAB9APDGFRB | |
| SCHEMBL8096178 | 0.72 | CYP2A6 (0.45) | TSHRLMNAALDH1A1CYP1A2MEN1 | |
| SCHEMBL22522189 | 0.72 | FFAR1 (0.50) | ALDH1A1CYP1A2TGM2L3MBTL1FFAR1 | |
| SCHEMBL2059540 | 0.72 | TSHR (0.50) | TNKS2POLBTSHRLMNAEGFR | |
| SCHEMBL22882621 | 0.71 | ALDH1A1 (0.36) | TNKS2POLBTSHRLMNAEGFR | |
| SCHEMBL4424144 | 0.71 | GPR52 (0.59) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16218017 | 0.70 | CYP4F2 (0.56) | LMNAKDM4EHPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362765-A2 | PERFUME SYSTEMS | The Procter & Gamble Company (US) | 2011-09-07 | — | — | EP | claimed |
| WO-2010065446-A2 | PERFUME SYSTEMS | THE PROCTER & GAMBLE COMPANY (US) | 2010-06-10 | — | — | WO | claimed |