Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.37 |
| ▸ | TGM2 | P21980 | 2/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14614108 | 0.79 | CYP4F2 (0.44) | IAPPTGM2PTGER1PTGER4PTGER3 | |
| SCHEMBL9308692 | 0.79 | TAAR1 (0.47) | IAPPTSHR | |
| SCHEMBL2441288 | 0.79 | TNKS2 (0.41) | TGM2GPR52ALDH1A1TSHRLMNA | |
| SCHEMBL2441467 | 0.78 | NOTUM (0.48) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL4348873 | 0.76 | FOLH1 (0.47) | ALDH1A1 | |
| SCHEMBL27405468 | 0.75 | PTGER4 (0.54) | PTGER1PTGER4PTGER3PTGER2LMNA | |
| SCHEMBL4423947 | 0.74 | MTNR1A (0.53) | THRBTHRATSHRMTNR1ALMNA | |
| SCHEMBL14613770 | 0.74 | LPAR1 (0.38) | THRBTHRAGABRA1GABRB2LMNA | |
| SCHEMBL4424144 | 0.72 | GPR52 (0.59) | GPR52ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL27720366 | 0.71 | GPR52 (0.58) | GPR52ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313474-B1 | AN OPTICAL ARTICLE EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1992-12-23 | — | — | EP | disclosed |
| EP-0313475-B1 | AN OPTICAL ARTICLE CONTAINING A TRANSMISSION MEDIUM EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1992-12-23 | — | — | EP | disclosed |
| EP-0349265-A2 | Electroluminescent devices | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-01-03 | — | — | EP | disclosed |
| US-4886339-A | MOLECULAR DIPOLES HELD IN POLAR ALIGNMENT BY A CROSSLINKED POLYMERIC BINDER; STABILITY | EASTMAN KODAK COMPANY (US) | 1989-12-12 | — | — | US | disclosed |
| EP-0313474-A2 | An optical article exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-04-26 | — | — | EP | disclosed |
| EP-0313475-A2 | An optical article containing a transmission medium exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-04-26 | — | — | EP | disclosed |
| US-4792208-A | POLAR ALIGNED NONCENTROSYMMETRIC MOLECULAR DIPOLES; SULFONYL MOIETY AS ELECTRON ACCEPTOR | EASTMAN KODAK COMPANY (US) | 1988-12-20 | — | — | US | disclosed |