Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 14/20 | 0.89 |
| ▸ | AXL | P30530 | 10/20 | 0.89 |
| ▸ | KDR | P35968 | 6/20 | 0.89 |
| ▸ | MERTK | Q12866 | 6/20 | 0.78 |
| ▸ | RET | P07949 | 3/20 | 0.73 |
| ▸ | KIT | P10721 | 3/20 | 0.73 |
| ▸ | FLT3 | P36888 | 3/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.73 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.73 |
| ▸ | FLT1 | P17948 | 3/20 | 0.72 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.72 |
| ▸ | AURKA | O14965 | 2/20 | 0.72 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.72 |
| ▸ | ABL1 | P00519 | 2/20 | 0.72 |
| ▸ | EGFR | P00533 | 2/20 | 0.72 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.72 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.72 |
| ▸ | LCK | P06239 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Exelixis SCHEMBL29693473 | 0.94 | MET (1.00) | METAXLKDRMERTKRET | |
| Exelixis SCHEMBL371899 | 0.94 | MET (1.00) | METAXLKDRMERTKRET | |
| SCHEMBL21688436 | 0.91 | AXL (0.88) | METAXLKDRMERTKRET | |
| SCHEMBL21688545 | 0.91 | AXL (0.88) | METAXLKDRMERTKRET | |
| SCHEMBL24413668 | 0.89 | MET (0.89) | METAXLKDRMERTKRET | |
| SCHEMBL4401190 | 0.88 | AXL (0.88) | METAXLKDRMERTKRET | |
| SCHEMBL29693431 | 0.88 | AXL (0.88) | METAXLKDRMERTKRET | |
| SCHEMBL29693534 | 0.88 | AXL (0.88) | METAXLKDRMERTKRET | |
| SCHEMBL372296 | 0.88 | AXL (0.88) | METAXLKDRMERTKRET | |
| SCHEMBL29693516 | 0.88 | AXL (0.88) | METAXLKDRMERTKRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220143183-A1 | PHOTOSWITCHABLE PROTACS AND SYNTHESIS AND USES THEREOF | NEW YORK UNIVERSITY | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220143183-A1 | PHOTOSWITCHABLE PROTACS AND SYNTHESIS AND USES THEREOF | MDM2, UBE3C, CUL1 | MET 1046/4885AXL 749/4885KDR 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.