Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 13/20 | 1.00 |
| ▸ | AXL | P30530 | 10/20 | 1.00 |
| ▸ | KDR | P35968 | 6/20 | 1.00 |
| ▸ | MERTK | Q12866 | 6/20 | 0.87 |
| ▸ | FLT3 | P36888 | 4/20 | 0.81 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.81 |
| ▸ | RET | P07949 | 3/20 | 0.81 |
| ▸ | KIT | P10721 | 3/20 | 0.81 |
| ▸ | FLT1 | P17948 | 3/20 | 0.81 |
| ▸ | AURKA | O14965 | 2/20 | 0.81 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.81 |
| ▸ | ABL1 | P00519 | 2/20 | 0.81 |
| ▸ | EGFR | P00533 | 2/20 | 0.81 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.81 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.81 |
| ▸ | LCK | P06239 | 2/20 | 0.81 |
| ▸ | LYN | P07948 | 2/20 | 0.81 |
| ▸ | HCK | P08631 | 2/20 | 0.81 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.81 |
| ▸ | BCR | P11274 | 2/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Exelixis SCHEMBL371899 | 1.00 | MET (1.00) | METAXLKDRMERTKFLT3 | |
| SCHEMBL24413668 | 0.94 | MET (0.89) | METAXLKDRMERTKFLT3 | |
| SCHEMBL24414026 | 0.94 | MET (0.89) | METAXLKDRMERTKFLT3 | |
| SCHEMBL4401190 | 0.94 | AXL (0.88) | METAXLKDRMERTKFLT3 | |
| SCHEMBL29693516 | 0.94 | AXL (0.88) | METAXLKDRMERTKFLT3 | |
| SCHEMBL29693534 | 0.94 | AXL (0.88) | METAXLKDRMERTKFLT3 | |
| SCHEMBL372296 | 0.94 | AXL (0.88) | METAXLKDRMERTKFLT3 | |
| SCHEMBL29693431 | 0.94 | AXL (0.88) | METAXLKDRMERTKFLT3 | |
| SCHEMBL19373358 | 0.94 | MET (0.88) | METAXLKDRMERTKFLT3 | |
| SCHEMBL24451294 | 0.93 | MET (0.87) | METAXLKDRMERTKFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115885035-A | Method for purifying cardiomyocytes | 千纸鹤治疗公司 | 2023-03-31 | — | — | CN | claimed |
| EP-3329918-B1 | C-MET MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2022-05-25 | — | — | EP | claimed |
| CN-115885035-A | Method for purifying cardiomyocytes | 千纸鹤治疗公司 | 2023-03-31 | — | — | CN | disclosed |
| EP-4123015-A1 | CARDIOMYOCYTE PURIFICATION METHOD | Orizuru Therapeutics, Inc. (JP) | 2023-01-25 | — | — | EP | disclosed |