Itaconate

Itaconate

SCHEMBL2441529

C=C(CC(=O)O)C(=O)O.C=COC(C)=O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.59
HSD17B10 Q99714 1/20 0.59
TET2 Q6N021 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Itaconate SCHEMBL9335169 0.90 ALOX15 (0.53) ALOX15HSD17B10
Dimethyl Maleate SCHEMBL27954483 0.90 ALOX15 (0.49) ALOX15HSD17B10
Malonic Acid SCHEMBL27696981 0.86 LDHA (0.43) ALOX15HSD17B10
SCHEMBL28065435 0.82 HSD17B10 (0.36) ALOX15HSD17B10TET2
SCHEMBL6027010 0.82 HSD17B10 (0.36) ALOX15HSD17B10TET2
Itaconate SCHEMBL1414108 0.82 ALOX15 (0.65) ALOX15HSD17B10TET2
Acetoacetic Acid SCHEMBL27553963 0.82 KDM4E (0.37) ALOX15HSD17B10
Itaconate SCHEMBL28030048 0.81 HSD17B10 (0.58) ALOX15HSD17B10TET2
SCHEMBL6062190 0.81 HSD17B10 (0.35) ALOX15HSD17B10TET2
Itaconate SCHEMBL29287922 0.79 ALOX15 (0.75) ALOX15HSD17B10TET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210767-A1 PARTICLE CONTAINING LIPID NANOPARTICLES AND METHOD FOR PRODUCING SAME RICOH COMPANY, LTD. (JP) 2023-07-06 US disclosed
EP-4169509-A1 PARTICLE CONTAINING LIPID NANOPARTICLES, AND METHOD FOR PRODUCING SAME Ricoh Company, Ltd. (JP) 2023-04-26 EP disclosed
CN-115297849-A Method for producing granules 株式会社理光 2022-11-04 CN disclosed
CN-114144171-A Granules, pharmaceutical compositions and methods for producing granules 株式会社理光 2022-03-04 CN disclosed
CN-113398076-A Sustained-release granules and process for producing the same 株式会社理光 2021-09-17 CN disclosed
CN-101277726-B Absorbent article comprising hydrophilic and hydrophobic regions SCA HYGIENE PROD AB 2012-05-30 CN disclosed
EP-1581692-B1 AMINO-FUNCTIONALIZED PULP FIBERS KIMBERLY CLARK CO (US) 2011-09-21 EP disclosed
US-7435266-B2 Polyvinylamine treatments to improve dyeing of cellulosic materials KIMBERLY-CLARK WORLDWIDE, INC. (US) 2008-10-14 US disclosed
CN-101277726-A Absorbent article comprising hydrophilic and hydrophobic regions SCA HYGIENE PROD AB (SE) 2008-10-01 CN disclosed
EP-1579071-B1 BICOMPONENT STRENGTHENING SYSTEM FOR PAPER KIMBERLY CLARK CO (US) 2008-07-16 EP disclosed
US-20030131962-A1 Fibrous materials treated with a polyvinylamine polymer KIMBERLY-CLARK WORLDWIDE, INC. 2003-07-17 US disclosed
WO-2003052206-A1 A PAPER PRODUCT COMPRISING A POLYVINYLAMINE POLYMER KIMBERLY-CLARK WORLDWIDE, INC. (US) 2003-06-26 WO disclosed
WO-2003052197-A2 POLYVINYLAMINE TREATMENTS TO IMPROVE DYEING OF CELLULOSIC MATERIALS KIMBERLY-CLARK WORLDWIDE, INC. (US) 2003-06-26 WO disclosed
CN-1304419-A Treatment of polyacrylonitrile polymers SOLUTIA INC (US) 2001-07-18 CN disclosed
EP-0753049-B1 DETERGENT COMPOSITIONS UNILEVER PLC (GB) 1999-12-22 EP disclosed
EP-0634428-B1 A method for manufacture of polymers NAT STARCH CHEM INVEST (US) 1998-10-21 EP disclosed
US-5399639-A Copolymers of itaconic acid with vinyl alcohol or acetate, anhydrous alcohol solvent NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1995-03-21 US disclosed
EP-0634428-A2 A method for manufacture of polymers National Starch and Chemical Investment Holding Corporation (US) 1995-01-18 EP disclosed
US-3998690-A SLURRIES THE PROCTER & GAMBLE COMPANY (US) 1976-12-21 US disclosed
US-3956117-A Cationic polymers for breaking oil-in-water emulsions NALCO CHEMICAL COMPANY (US) 1976-05-11 US disclosed