Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TET3 | O43151 | 1/20 | 0.33 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Itaconate SCHEMBL28248912 | 0.90 | HSD17B10 (0.62) | HSD17B10ALOX15ALDH1A1LDHASRR | |
| Itaconate SCHEMBL2564169 | 0.87 | ALOX15 (0.65) | HSD17B10ALOX15ALDH1A1LDHASRR | |
| Itaconate SCHEMBL31425252 | 0.85 | ALOX15 (0.62) | HSD17B10ALOX15ALDH1A1LDHASRR | |
| Itaconate SCHEMBL5429101 | 0.85 | ALOX15 (0.62) | HSD17B10ALOX15ALDH1A1LDHASRR | |
| Itaconate SCHEMBL2945767 | 0.85 | ALOX15 (0.62) | HSD17B10ALOX15ALDH1A1LDHASRR | |
| Itaconate SCHEMBL5447650 | 0.85 | ALOX15 (0.68) | HSD17B10ALOX15LDHASRRTET2 | |
| Itaconate SCHEMBL15419775 | 0.85 | ALDH1A1 (0.62) | HSD17B10ALOX15ALDH1A1LDHASRR | |
| Itaconate SCHEMBL286967 | 0.84 | ALOX15 (0.75) | HSD17B10ALOX15LDHASRRTET2 | |
| Itaconate SCHEMBL21523 | 0.84 | — | — | |
| Itaconate SCHEMBL29886131 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104822832-A | Itaconic acid and methyl itaconate production | DSM IP ASSETS BV | 2015-08-05 | — | — | CN | disclosed |