Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369489 | 0.80 | ALDH1A1 (0.49) | MMP2CYP1A2KDM4EGAAGLA | |
| SCHEMBL4251404 | 0.78 | MMP2 (0.50) | MMP2MAPK1TSHRCYP1A2KDM4E | |
| SCHEMBL20534022 | 0.77 | MMP2 (0.49) | MMP2MAPK1TSHRCYP1A2KDM4E | |
| SCHEMBL18626490 | 0.77 | MMP2 (0.49) | MMP2MAPK1TSHRCYP1A2KDM4E | |
| SCHEMBL11392770 | 0.77 | MMP2 (0.49) | MMP2MAPK1TSHRCYP1A2KDM4E | |
| SCHEMBL20630811 | 0.77 | MMP2 (0.60) | MMP2MAPK1TSHRCYP1A2KDM4E | |
| SCHEMBL14738345 | 0.75 | MMP2 (0.48) | MMP2MAPK1TSHRCYP1A2KDM4E | |
| SCHEMBL14744177 | 0.75 | MMP2 (0.67) | MMP2MAPK1TSHRCYP1A2KDM4E | |
| SCHEMBL7424608 | 0.74 | MMP2 (0.61) | MMP2MAPK1TSHRCYP1A2KDM4E | |
| SCHEMBL8225066 | 0.74 | MMP2 (0.50) | MMP2MAPK1TSHRCYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022095989-A1 | P300 INHIBITORS AND USE THEREOF IN MEDICINE | 贝达药业股份有限公司 | 2022-05-12 | — | — | WO | disclosed |