SCHEMBL369489

SCHEMBL369489

CCOC(=O)c1cnc(N)[nH]1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
LMNA P02545 3/20 0.47
KDM4E B2RXH2 6/20 0.45
HPGD P15428 4/20 0.45
HTT P42858 1/20 0.45
RECQL P46063 1/20 0.45
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAOA P21397 1/20 0.43
HSP90AA1 P07900 1/20 0.43
RAB9A P51151 5/20 0.42
NPC1 O15118 4/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
HSD17B10 Q99714 2/20 0.42
MMP2 P08253 1/20 0.41
MMP13 P45452 1/20 0.41
MAPT P10636 4/20 0.41
GAA P10253 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21238310 0.83 KDM4E (0.44) ALDH1A1MEN1KMT2ALMNAKDM4E
SCHEMBL8818379 0.82 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ALMNAKDM4E
SCHEMBL24415499 0.80 MMP2 (0.49) ALDH1A1MEN1KMT2ALMNAKDM4E
SCHEMBL1437509 0.79 KDM4E (0.44) ALDH1A1MEN1KMT2ALMNAKDM4E
SCHEMBL18626491 0.79 ALOX15 (0.47) ALDH1A1MEN1KMT2ALMNAKDM4E
SCHEMBL20534000 0.79 KDM4E (0.45) ALDH1A1MEN1KMT2ALMNAKDM4E
SCHEMBL7997265 0.79 KDM4E (0.55) ALDH1A1MEN1KMT2ALMNAKDM4E
SCHEMBL5032446 0.77 KDM4E (0.42) ALDH1A1MEN1KMT2ALMNAKDM4E
SCHEMBL12408070 0.77 KDM6B (0.44) ALDH1A1MEN1KMT2ALMNAKDM4E
SCHEMBL20970388 0.77 PLG (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324814-A Extractant for enriching metal ions and preparation method and application thereof 山东共聚有机硅技术研究院有限公司 2024-07-12 CN claimed
CN-113817164-B Hypoxic sensitive drug carrier polymer and preparation method and application thereof 北京化工大学 2022-11-29 CN claimed
CN-113817164-A Hypoxic sensitive drug carrier polymer and preparation method and application thereof 北京化工大学 2021-12-21 CN claimed
WO-2025151517-A1 THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS ASSOCIATED WITH MISSFOLDING OF ALPHA-SYNUCLEIN PROTEIN WAVEBREAK THERAPEUTICS LIMITED (US) 2025-07-17 WO disclosed
CN-118955393-A 2, 4-Dinitrophenoxy compound and preparation method thereof 江南大学 2024-11-15 CN disclosed
CN-118324814-A Extractant for enriching metal ions and preparation method and application thereof 山东共聚有机硅技术研究院有限公司 2024-07-12 CN disclosed
CN-117756848-A TH-302 derivative and preparation method thereof 常州大学 2024-03-26 CN disclosed
CN-113831337-B GLP-1 receptor agonist, and pharmaceutical composition and use thereof 广州市恒诺康医药科技有限公司 2023-03-24 CN disclosed
CN-113817164-B Hypoxic sensitive drug carrier polymer and preparation method and application thereof 北京化工大学 2022-11-29 CN disclosed
CN-113831337-A GLP-1 receptor agonist, and pharmaceutical composition and use thereof 广州市恒诺康医药科技有限公司 2021-12-24 CN disclosed
CN-113817164-A Hypoxic sensitive drug carrier polymer and preparation method and application thereof 北京化工大学 2021-12-21 CN disclosed
WO-2012007409-A1 N-SUBSTITUTED PYRROLIDINES F. HOFFMANN-LA ROCHE AG (CH) 2012-01-19 WO disclosed
US-20120010235-A1 N-SUBSTITUTED PYRROLIDINES CHU XIN-JIE (US) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010235-A1 N-SUBSTITUTED PYRROLIDINES H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PKD1, TP53 ALDH1A1 799/4885MEN1 966/4885KMT2A 3481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.