Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 2/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12758232 | 0.94 | PTPN1 (0.43) | APPPTPN1ACP1CDC25BALDH1A1 | |
| SCHEMBL14456205 | 0.90 | APP (0.41) | APPPTPN1ACP1CDC25BALDH1A1 | |
| SCHEMBL21128873 | 0.83 | APP (0.43) | APPPTPN1ACP1CDC25BALDH1A1 | |
| SCHEMBL12758237 | 0.83 | APP (0.40) | APPPTPN1ACP1CDC25BALDH1A1 | |
| SCHEMBL4544722 | 0.77 | APP (0.41) | APPALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL9889241 | 0.74 | APP (0.50) | APPPTPN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9889238 | 0.73 | APP (0.44) | APPALDH1A1CYP1A2CYP2C19CRHBP | |
| SCHEMBL19240037 | 0.72 | ALDH1A1 (0.39) | APPALDH1A1KMT2AMEN1POLB | |
| SCHEMBL9892476 | 0.71 | APP (0.37) | APPALDH1A1CRHBPCRHR2L3MBTL1 | |
| SCHEMBL12758250 | 0.69 | PTGS1 (0.35) | POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144759-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-05-12 | — | — | US | disclosed |
| US-20220144769-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144769-A1 | COMPOUND | CBR3, SFXN3, CBR1 | APP 3557/4885PTPN1 2875/4885ACP1 3606/4885 |
| US-20220144759-A1 | COMPOUND | SFXN3, SFXN1, CBR3 | APP 3073/4885PTPN1 2858/4885ACP1 1780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.