Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12623894 | 0.87 | ALDH1A1 (0.42) | ALDH1A1KDM1AMAOBRCOR1GFER | |
| SCHEMBL12623893 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KDM1AMAOBRCOR1GFER | |
| SCHEMBL20019696 | 0.78 | — | — | |
| SCHEMBL12623896 | 0.76 | ALDH1A1 (0.40) | ALDH1A1KDM1AMAOBRCOR1GFER | |
| SCHEMBL12623907 | 0.76 | LMNA (0.43) | ALDH1A1GFERNPC1MAPTRAB9A | |
| SCHEMBL12622192 | 0.76 | ALDH1A1 (0.45) | ALDH1A1GFERNPC1MAPTRAB9A | |
| SCHEMBL23160703 | 0.71 | NPC1 (0.41) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL12626420 | 0.71 | GPR119 (0.43) | — | |
| SCHEMBL12623932 | 0.69 | ALDH1A1 (0.56) | ALDH1A1KDM1AMAOBRCOR1GFER | |
| SCHEMBL12626404 | 0.66 | LMNA (0.43) | ALDH1A1GFERNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022098700-A1 | INHIBITING AN IMMUNE RESPONSE MEDIATED BY ONE OR MORE OF TLR2, RAGE, CCR5, CXCR4 AND CD4 | CASSAVA SCIENCES, INC. (US) | 2022-05-12 | — | — | WO | disclosed |