Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936714 | 0.75 | SLC6A9 (0.34) | — | |
| SCHEMBL10355569 | 0.72 | LMNA (0.36) | LMNACYP2C9 | |
| SCHEMBL4743603 | 0.71 | LMNA (0.40) | LMNACYP2C9 | |
| SCHEMBL7292447 | 0.71 | LMNA (0.40) | LMNACYP2C9 | |
| SCHEMBL3997073 | 0.69 | LMNA (0.39) | LMNACYP2C9 | |
| SCHEMBL503732 | 0.69 | LMNA (0.35) | LMNACYP2C9 | |
| SCHEMBL8781384 | 0.69 | LMNA (0.35) | LMNACYP2C9 | |
| SCHEMBL1638503 | 0.68 | LMNA (0.38) | LMNACYP2C9 | |
| SCHEMBL5493343 | 0.68 | LMNA (0.34) | LMNACYP2C9 | |
| SCHEMBL7349981 | 0.66 | LMNA (0.32) | LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120294938-A1 | PHARMACEUTICAL PREPARATION FOR ORAL ADMINISTRATION WITH CONTROLLED ACTIVE INGREDIENT RELEASE IN THE SMALL INTESTINE AND METHOD FOR ITS PRODUCTION | Dr. R. Pflefger Chemische Fabrik GmbH (DE) | 2012-11-22 | — | — | US | claimed |
| EP-1880718-B1 | Pharmaceutical preparation for oral administration with controlled drug release in the small intestine colon and process of prepartion thereof | PFLEGER R CHEM FAB (DE) | 2011-09-21 | — | — | EP | claimed |
| US-20090285891-A1 | Pharmaceutical preparation for oral administration with controlled active ingredient release in the small intestine and method for its production | DR. R. PFLEGER CHEMISCHE FABRIK GMBH (DE) | 2009-11-19 | — | — | US | claimed |
| US-20120294938-A1 | PHARMACEUTICAL PREPARATION FOR ORAL ADMINISTRATION WITH CONTROLLED ACTIVE INGREDIENT RELEASE IN THE SMALL INTESTINE AND METHOD FOR ITS PRODUCTION | Dr. R. Pflefger Chemische Fabrik GmbH (DE) | 2012-11-22 | — | — | US | disclosed |
| US-8221787-B2 | Pharmaceutical preparation for oral administration with controlled active ingredient release in the small intestine and method for its production | Dr. Robert Pfleger Chemische Fabrik GmbH (DE) | 2012-07-17 | — | — | US | disclosed |
| US-20090285891-A1 | Pharmaceutical preparation for oral administration with controlled active ingredient release in the small intestine and method for its production | DR. R. PFLEGER CHEMISCHE FABRIK GMBH (DE) | 2009-11-19 | — | — | US | disclosed |