SCHEMBL5493343

SCHEMBL5493343

CN1C2CCC1(C(N)=O)CC(O)C2

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
CYP2C9 P11712 1/20 0.34
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL503732 0.85 LMNA (0.35) LMNACYP2C9
SCHEMBL8781384 0.85 LMNA (0.35) LMNACYP2C9
SCHEMBL19257963 0.84 POLB (0.31) POLB
SCHEMBL7349981 0.81 LMNA (0.32) LMNACYP2C9POLB
SCHEMBL10355569 0.81 LMNA (0.36) LMNACYP2C9
SCHEMBL19257640 0.80 POLB (0.32) POLB
SCHEMBL7265277 0.75 LMNA (0.39) LMNA
SCHEMBL5784031 0.70
SCHEMBL1380065 0.70
SCHEMBL7292447 0.69 LMNA (0.40) LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020151501-A1 Compounds having growth hormone releasing activity BOWERS CYRIL Y (US) 2002-10-17 US claimed
EP-1159292-A2 COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY Administrators of The Tulane Educational Fund (US) 2001-12-05 EP claimed
WO-2000009537-A2 COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2000-02-24 WO claimed
CN-112603926-A Atropine inosine eye drops for treating myopia and preparation method thereof 河南合智医药科技有限公司 2021-04-06 CN disclosed
CN-111039852-A N-ethylpyridine methylamine hydrochloride crystal, preparation process and application thereof in preparation of tropicamide 卡博金艾美斯医药(上海)有限公司 2020-04-21 CN disclosed
CN-110950795-A N-ethylpyridine methylamine methanesulfonate crystal, preparation process and application thereof in preparation of tropicamide 卡博金艾美斯医药(上海)有限公司 2020-04-03 CN disclosed
CN-110872251-A N-ethylpyridine methylamine trifluoroacetate and crystal, preparation process and application thereof 卡博金艾美斯医药(上海)有限公司 2020-03-10 CN disclosed
CN-103159672-A Preparation method of tropine amide HUNAN IVEN BIO TECHNOLOGY CO LTD 2013-06-19 CN disclosed
CN-103159672-A Preparation method of tropine amide HUNAN IVEN BIO TECHNOLOGY CO LTD 2013-06-19 CN disclosed
US-7250399-B2 Compounds having growth hormone releasing activity THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2007-07-31 US disclosed
US-20020161013-A1 Method of local anesthesia and analgesia WEX MEDICAL INTRUMENTATION CO., LTD. (HK) 2002-10-31 US disclosed
US-6468974-B1 OLIGOPEPTIDES THAT PROVIDE DESIRABLE IN VITRO AND IN VIVO GROWTH HORMONE RELEASING ACTIVITY AND HAVE AT LEAST ONE OTHER DESIRABLE BIOLOGICAL ACTIVITY SUCH AS INCREASED RETENTION TIME THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND 2002-10-22 US disclosed
US-20020151501-A1 Compounds having growth hormone releasing activity BOWERS CYRIL Y (US) 2002-10-17 US disclosed
EP-1159292-A2 COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY Administrators of The Tulane Educational Fund (US) 2001-12-05 EP disclosed
WO-2000009537-A2 COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2000-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151501-A1 Compounds having growth hormone releasing activity GHSR, GHRHR, NPY1R LMNA 4062/4885CYP2C9 4153/4885POLB 2047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.