Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20043720 | 0.83 | NPC1 (0.36) | NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL24199011 | 0.69 | L3MBTL1 (0.40) | L3MBTL1MAPT | |
| SCHEMBL21469472 | 0.67 | NPC1 (0.39) | NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL17586593 | 0.67 | GAA (0.37) | L3MBTL1MAPT | |
| SCHEMBL12795882 | 0.66 | ADAM17 (0.44) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL16327606 | 0.64 | L3MBTL1 (0.47) | NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL14031499 | 0.63 | NPC1 (0.36) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL18499723 | 0.61 | NPC1 (0.34) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL18522793 | 0.61 | ALDH1A1 (0.33) | MAPT | |
| SCHEMBL6388210 | 0.61 | NPC1 (0.44) | NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099153-A1 | NOVEL VHL SMALL MOLECULE PROBES | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2022-05-12 | — | — | WO | disclosed |