SCHEMBL24418686

SCHEMBL24418686

O=c1ccc2c(-c3ccccc3CO)c3ccc(NCC(F)(F)F)cc3oc-2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.45
USP2 O75604 4/20 0.44
MEN1 O00255 3/20 0.44
POLB P06746 3/20 0.44
KMT2A Q03164 3/20 0.44
ATM Q13315 1/20 0.44
PLEC Q15149 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.38
DNASE1L3 Q13609 1/20 0.37
PRMT1 Q99873 1/20 0.37
CA9 Q16790 6/20 0.36
CA1 P00915 5/20 0.36
CA2 P00918 5/20 0.36
CA12 O43570 2/20 0.36
CA14 Q9ULX7 1/20 0.36
MAOB P27338 5/20 0.36
HDAC6 Q9UBN7 1/20 0.36
ALB P02768 1/20 0.35
ALPL P05186 1/20 0.35
ALPI P09923 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14433567 0.80 MEN1 (0.68) USP2MEN1POLBKMT2AATM
SCHEMBL20256014 0.79 USP2 (0.55) USP2MEN1POLBKMT2AATM
SCHEMBL15483658 0.79 USP2 (0.51) USP2MEN1POLBKMT2AATM
SCHEMBL29707441 0.77 ALDH1A1 (0.47) USP2MEN1POLBKMT2AATM
SCHEMBL15483870 0.77 ALDH1A1 (0.47) USP2MEN1POLBKMT2AATM
SCHEMBL20362457 0.76 KDM4E (0.50) ARUSP2MEN1POLBKMT2A
SCHEMBL10021384 0.73 USP2 (0.45) USP2MEN1POLBKMT2AATM
SCHEMBL10021390 0.72 USP2 (0.44) USP2MEN1POLBKMT2AATM
SCHEMBL15743587 0.72 FTO (0.42) ARUSP2MEN1POLBKMT2A
SCHEMBL12708320 0.71 MEN1 (0.68) USP2MEN1POLBKMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220186286-A1 FLUORESCENT PROBE FOR DETECTING ACTIVATION OF SIALIDASE UNIV TOKYO (JP) 2022-06-16 US disclosed
US-20220145407-A1 METHOD AND KIT FOR DETECTING INFLUENZA VIRUS, AND METHOD FOR DIAGNOSING INFLUENZA VIRUS INFECTION JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220186286-A1 FLUORESCENT PROBE FOR DETECTING ACTIVATION OF SIALIDASE NEU1, NEU3, NEU2 AR 2678/4885USP2 3019/4885MEN1 2869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.