Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14438657 | 0.83 | ALDH1A1 (0.46) | KDM4EHSD17B10ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL27057530 | 0.80 | KDM4E (0.44) | KDM4EHSD17B10ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL25824412 | 0.79 | ALDH1A1 (0.43) | KDM4EHSD17B10ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL19841641 | 0.76 | GRIN2D (0.39) | KMT2ACYP2C9MAPTCYP1A2CYP2C19 | |
| SCHEMBL23240427 | 0.74 | GRIA1 (0.41) | HSD17B10ALDH1A1KMT2ACYP2C9MAPT | |
| SCHEMBL14438658 | 0.74 | ALDH1A1 (0.44) | KDM4EHSD17B10ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL2028863 | 0.69 | KDM4E (0.48) | KDM4EHSD17B10ALDH1A1KMT2AGAA | |
| SCHEMBL22289091 | 0.67 | TK1 (0.70) | CYP1A2LMNANPSR1 | |
| SCHEMBL3293016 | 0.65 | ALDH1A1 (0.52) | KDM4EHSD17B10ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL23897613 | 0.65 | MAPK1 (0.51) | ALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2022099159-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | WO | disclosed |