Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14438657 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10HTTCYP2C19 | |
| SCHEMBL20870266 | 0.81 | SMN1; SMN2 (0.38) | ALDH1A1KDM4EHSD17B10HTTCYP2C19 | |
| SCHEMBL24420115 | 0.79 | KDM4E (0.47) | ALDH1A1KDM4EHSD17B10HTTCYP2C19 | |
| SCHEMBL21637955 | 0.78 | SMN1; SMN2 (0.36) | ALDH1A1HTTCYP2C19SMN1; SMN2GAA | |
| SCHEMBL18858876 | 0.78 | MET (0.39) | ALDH1A1HTTCYP2C19SMN1; SMN2 | |
| SCHEMBL27057530 | 0.78 | KDM4E (0.44) | ALDH1A1KDM4EHSD17B10HTTCYP2C19 | |
| SCHEMBL10137841 | 0.77 | SMN1; SMN2 (0.41) | ALDH1A1HTTCYP2C19SMN1; SMN2GAA | |
| SCHEMBL14438658 | 0.75 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10HTTCYP2C19 | |
| SCHEMBL26608016 | 0.71 | ALDH1A1 (0.51) | ALDH1A1KDM4EHTTCYP2C19KMT2A | |
| SCHEMBL24450047 | 0.69 | DAO (0.39) | ALDH1A1KDM4EHSD17B10HTTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |