Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24420689 | 0.87 | RNASE1 (0.43) | — | |
| SCHEMBL24420138 | 0.86 | TK1 (0.44) | — | |
| SCHEMBL15066132 | 0.83 | TK1 (0.57) | — | |
| SCHEMBL15066131 | 0.83 | TK1 (0.57) | — | |
| SCHEMBL17283457 | 0.83 | TK1 (0.57) | — | |
| SCHEMBL18873431 | 0.83 | TK1 (0.57) | — | |
| SCHEMBL27058571 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27054118 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL25824045 | 0.80 | P2RY2 (0.48) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31228064 | 0.79 | RNASE1 (0.48) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220428-A1 | COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2022099159-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | WO | disclosed |