Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.65 |
| ▸ | DHFR | P00374 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19308099 | 1.00 | TK1 (0.65) | TK1DHFRPOLB | |
| SCHEMBL27054363 | 1.00 | TK1 (0.65) | TK1DHFRPOLB | |
| SCHEMBL6379327 | 0.92 | TK1 (0.67) | TK1DHFR | |
| SCHEMBL25752530 | 0.91 | TK1 (0.70) | TK1DHFRPOLB | |
| SCHEMBL316663 | 0.90 | TK1 (0.65) | TK1DHFRPOLB | |
| SCHEMBL658884 | 0.90 | TK1 (0.65) | TK1DHFR | |
| SCHEMBL7537554 | 0.90 | TK1 (0.65) | TK1DHFRPOLB | |
| SCHEMBL3272720 | 0.89 | TK1 (0.63) | TK1DHFRPOLB | |
| SCHEMBL4542151 | 0.89 | TK1 (0.63) | TK1DHFR | |
| SCHEMBL2295 | 0.89 | TK1 (0.63) | TK1DHFRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| WO-2023220428-A1 | COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2022099159-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | WO | disclosed |