SCHEMBL316663

SCHEMBL316663

Cc1cn([C@H]2C[C@H](O)[C@@H](C(N)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TK1 P04183 5/20 0.65
DHFR P00374 1/20 0.52
POLB P06746 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6379327 0.92 TK1 (0.67) TK1DHFR
SCHEMBL658884 0.90 TK1 (0.65) TK1DHFR
SCHEMBL27054363 0.90 TK1 (0.65) TK1DHFRPOLB
SCHEMBL7537554 0.90 TK1 (0.65) TK1DHFRPOLB
SCHEMBL19308099 0.90 TK1 (0.65) TK1DHFRPOLB
SCHEMBL24420522 0.90 TK1 (0.65) TK1DHFRPOLB
SCHEMBL2295 0.89 TK1 (0.63) TK1DHFRPOLB
SCHEMBL3272720 0.89 TK1 (0.63) TK1DHFRPOLB
SCHEMBL4542151 0.89 TK1 (0.63) TK1DHFR
SCHEMBL25752530 0.89 TK1 (0.70) TK1DHFRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117512038-A Sansansamycin derivatives and application thereof 中国医学科学院医药生物技术研究所 2024-02-06 CN claimed
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 US disclosed
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS OPENTRONS LABWORKS INC (US) 2026-03-05 US disclosed
US-20250313889-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-10-09 US disclosed
CN-117343990-B Method and kit for determining target polynucleotide and probe set 牛津纳米孔科技公开有限公司 2025-05-30 CN disclosed
CN-112703256-B Method for determining polymer sequences 牛津纳米孔科技公开有限公司 2024-09-03 CN disclosed
US-20240117337-A1 METHODS AND POLYNUCLEOTIDES FOR AMPLIFYING A TARGET POLYNUCLEOTIDE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-04-11 US disclosed
US-20240076719-A9 METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-03-07 US disclosed
CN-117512038-A Sansansamycin derivatives and application thereof 中国医学科学院医药生物技术研究所 2024-02-06 CN disclosed
CN-117343990-A Method and kit for determining target polynucleotide and probe set 牛津纳米孔科技公开有限公司 2024-01-05 CN disclosed
US-6200748-B1 OLIGONUCLEOTIDE SEQUENCES AND A TEMPLATE; FOR MONITORING AND DETECTING NUCLEOTIDE SEQUENCES; FOR THE ANALYSIS OF NUCLEIC ACIDS CALIFORNIA INSTITUTE OF TECHNOLOGY 2001-03-13 US disclosed
WO-2000077179-A2 HUMAN POLY(ADP-RIBOSE) POLYMERASE 2 MATERIALS AND METHODS ICOS CORPORATION (US) 2000-12-21 WO disclosed
US-5821058-A SEPARATING PLURALITY OF POLYNUCLEOTIDES, EACH TAGGED WITH CHROMOPHORE OR FLUOROPHORE, BY ELECTROPHORESIS, DETECTING CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-10-13 US disclosed
US-5552540-A NONRADIOACTIVE LABELS HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) 1996-09-03 US disclosed
EP-0366685-B1 NUCLEOSIDE DERIVATIVES FLOREY HOWARD INST (AU) 1994-10-19 EP disclosed
US-5171534-A Electrophoretic analysis of DNA fragments tagged with fluorophore; absorption or fluorescent photometer CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1992-12-15 US disclosed
EP-0366685-A4 NUCLEOSIDE DERIVATIVES 1991-03-20 EP disclosed
EP-0366685-A1 NUCLEOSIDE DERIVATIVES. FLOREY HOWARD INST (AU) 1990-05-09 EP disclosed
WO-1988010264-A1 NUCLEOSIDE DERIVATIVES HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY (AU) 1988-12-29 WO disclosed
US-3791928-A PURIFICATION OF THYMIDINE KINASE MAX PLANCK GESELLSCHAFT 1974-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584168-B2 Sample preparation method POLN, POLRMT, POLM TK1 472/4885DHFR 2012/4885POLB 4/4885
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS POLRMT, POLL, SARS1 TK1 1713/4885DHFR 2190/4885POLB 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.