SCHEMBL2295

SCHEMBL2295

Cc1cn([C@H]2C[C@H](O)[C@@H](C(O)F)O2)c(=O)[nH]c1=O

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TK1 P04183 5/20 0.63
DHFR P00374 1/20 0.51
POLB P06746 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6379327 0.91 TK1 (0.67) TK1DHFR
SCHEMBL19308099 0.89 TK1 (0.65) TK1DHFRPOLB
SCHEMBL316663 0.89 TK1 (0.65) TK1DHFRPOLB
SCHEMBL7537554 0.89 TK1 (0.65) TK1DHFRPOLB
SCHEMBL27054363 0.89 TK1 (0.65) TK1DHFRPOLB
SCHEMBL24420522 0.89 TK1 (0.65) TK1DHFRPOLB
SCHEMBL658884 0.89 TK1 (0.65) TK1DHFR
SCHEMBL3272720 0.88 TK1 (0.63) TK1DHFRPOLB
SCHEMBL4542151 0.88 TK1 (0.63) TK1DHFR
SCHEMBL25752530 0.88 TK1 (0.70) TK1DHFRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 991 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025226286-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS IMAGING OF MULTIPLE POSITRON EMISSION TOMOGRAPHY (PET) TRACERS MULTIF UNCTIONAL IMAGING LLC (US) 2025-10-30 WO claimed
US-20250329024-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS IMAGING OF MULTIPLE POSITRON EMISSION TOMOGRAPHY (PET) TRACERS MultiFunctional Imaging LLC (US) 2025-10-23 US claimed
EP-4344736-A2 METHODS FOR CALCULATING BOUNDED DOSE-VOLUME HISTOGRAMS (DVH) FOR EVALUATING A TREATMENT PLAN RefleXion Medical, Inc. (US) 2024-04-03 EP claimed
US-20230414704-A1 Compositions Containing a Pharmacophore with Selectivity to Diseased Tissue and Methods of Making Same SANFORD-BURNHAM MEDICAL DISCOVERY INSTITUTE 2023-12-28 US claimed
CN-116916936-A Compositions and methods for delivering RNA 再生技术有限责任公司 2023-10-20 CN claimed
EP-3218333-B1 FLUORIDE TRAPPING ARRANGEMENT GE HEALTHCARE LTD (GB) 2023-06-07 EP claimed
US-11648418-B2 Systems and methods for biological adaptive radiotherapy REFLEXION MEDICAL, INC. (US) 2023-05-16 US claimed
US-20230068052-A1 ELUENT SOLUTION GE HEALTHCARE LTD (GB) 2023-03-02 US claimed
CN-109154671-B Radioactivity detection 赫尔大学 2022-10-04 CN claimed
US-11021497-B2 Compositions and methods for synthesis of phosphorylated molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-06-01 US claimed
WO-2000047198-A2 USE OF SUBSTITUTED-1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL COMPOUNDS FOR TREATING HEPATITIS VIRUS INFECTIONS G.D. SEARLE & CO. (US) 2000-08-17 WO claimed
WO-1999058723-A1 HETERODUPLEX MUTATIONAL VECTORS AND USE THEREOF IN BACTERIA KIMERAGEN, INC. (US) 1999-11-18 WO claimed
CN-1214629-A Solid immediate release dosage form and process for preparing same BOEHRINGER MANNHEIM GMBH (DE) 1999-04-21 CN claimed
US-5869097-A OSMOTIC CAPLET EXIT FOR DELIVERING A PRESELECTED DOSE OF DRUG ALZA CORPORATION (US) 1999-02-09 US claimed
US-5846987-A Retroviral protease inhibiting compounds ABBOTT LABORATORIES (US) 1998-12-08 US claimed
US-5635523-A ADMINISTERING MIXTURE OF 5-(N-(N-((N-METHYL-N-((2-ISOPROPYL-4-THIAZOLYL)METHYL) -AMINO)CARBONYL)VALINYL)AMINO)-2-(N-((5-THIAZOLYL)METHOXYCARBONYL)AMINO)-1,6-DIPHENYL-3-HYDROXYHEXANE OR SALT AND REVERSE TRASCRIPTASE INHIBITOR ABBOTT LABORATORIES (US) 1997-06-03 US claimed
EP-0727419-A2 Retroviral protease inhibiting compounds Abbott Laboratories (US) 1996-08-21 EP claimed
CN-1032258-C Phospholipid derivatives of nucleosides, processes for prepn. thereof and use thereof as antiviral medicaments BOCHRINGER MANNHEIM GMBH (DE) 1996-07-10 CN claimed
US-5358721-A Antiviral therapy ALZA CORPORATION (US) 1994-10-25 US claimed
CN-1059149-A New nucleoside phospholipid derivant, they method for making and as the application of antiviral BOEHRINGER MANNHEIM GMBH (DE) 1992-03-04 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230068052-A1 ELUENT SOLUTION ABCB11, IPO5, PFAS TK1 397/4885DHFR 990/4885POLB 305/4885
US-11021497-B2 Compositions and methods for synthesis of phosphorylated molecules PIK3CA, CHAMP1, TYMP TK1 22/4885DHFR 771/4885POLB 104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.