Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691173 | 0.85 | DPP4 (0.50) | HDAC4HDAC1HDAC6AAK1GAA | |
| SCHEMBL12463556 | 0.83 | EPHX1 (0.45) | HDAC4HDAC1HDAC6AAK1GAA | |
| SCHEMBL22501529 | 0.83 | EPHX1 (0.45) | HDAC4HDAC1HDAC6AAK1GAA | |
| SCHEMBL9099994 | 0.82 | AAK1 (0.40) | HDAC4HDAC1HDAC6AAK1GAA | |
| SCHEMBL9099990 | 0.82 | AAK1 (0.40) | HDAC4HDAC1HDAC6AAK1GAA | |
| SCHEMBL18212482 | 0.81 | KMT2A (0.40) | ELANECTSSCTSKCA1CA2 | |
| SCHEMBL6698692 | 0.81 | DPP4 (0.51) | HDAC4HDAC1HDAC6AAK1GAA | |
| SCHEMBL6698698 | 0.81 | DPP4 (0.51) | HDAC4HDAC1HDAC6AAK1GAA | |
| SCHEMBL6813595 | 0.80 | EPHX1 (0.43) | HDAC4HDAC1HDAC6AAK1GAA | |
| SCHEMBL6813596 | 0.80 | EPHX1 (0.43) | HDAC4HDAC1HDAC6AAK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220142976-A1 | Nitrile-Containing Antiviral Compounds | PFIZER INC. (US) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220142976-A1 | Nitrile-Containing Antiviral Compounds | ACE2, NOS2, EIF2AK2 | HDAC4 1823/4885HDAC1 1496/4885HDAC6 1127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.