Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | PTPRC | P08575 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24627654 | 0.91 | ALDH1A1 (0.47) | ALDH1A1PTPN1PTPRCHCAR2TDP1 | |
| SCHEMBL23657539 | 0.84 | ALDH1A1 (0.46) | ALDH1A1PTPN1PTPRCHCAR2TDP1 | |
| SCHEMBL29220153 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL29220126 | 0.84 | ALDH1A1 (0.50) | ALDH1A1PTPN1PTPRCHCAR2TDP1 | |
| SCHEMBL1273767 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL19388495 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL20150647 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL15114507 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL8688641 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1PTPN1PTPRCHCAR2TDP1 | |
| SCHEMBL14847458 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813471-A | Trifluoromethyl alkynylation reaction of photocatalytic 1, 6-diene and application | 郑州大学 | 2023-09-29 | — | — | CN | disclosed |
| US-20220219155-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2022-07-14 | — | — | US | disclosed |
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | PPOX, CYBA, CYBB | ALDH1A1 1395/4885PTPN1 4647/4885PTPRC 3769/4885 |
| US-20220219155-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | PPOX, CYBA, CYBB | ALDH1A1 1395/4885PTPN1 4647/4885PTPRC 3769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.