Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12583454 | 0.83 | AKR1B10 (0.49) | ESR1ESR2AKR1B10AKR1C4AKR1C3 | |
| SCHEMBL16186302 | 0.81 | CYP2C19 (0.34) | CYP2C19CCR2ESR1ESR2ALDH1A1 | |
| SCHEMBL17282342 | 0.75 | AKR1B10 (0.47) | ESR1ESR2AKR1B10AKR1C4AKR1C3 | |
| SCHEMBL3587056 | 0.73 | MAOB (0.52) | ALDH1A1MAOBMAOAACHETDP1 | |
| SCHEMBL9848314 | 0.73 | ALDH1A1 (0.36) | CYP2C19CCR2ESR1ESR2ALDH1A1 | |
| SCHEMBL17282333 | 0.71 | AKR1B10 (0.43) | ALDH1A1AKR1B10AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL26435127 | 0.71 | ESR1 (0.69) | CYP2C19CCR2ESR1ESR2ALDH1A1 | |
| SCHEMBL21387376 | 0.71 | ESR1 (0.69) | CYP2C19CCR2ESR1ESR2ALDH1A1 | |
| SCHEMBL19675546 | 0.69 | ESR1 (0.33) | ESR1ESR2LMNA | |
| SCHEMBL17031428 | 0.68 | OPRM1 (0.46) | CYP2C19MGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998070-A1 | MIR-124 AS A BIOMARKER FOR THE TREATMENT OF INFLAMMATORY DISEASES | ABIVAX (FR) | 2022-05-18 | — | — | EP | disclosed |