Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 6/20 | 0.34 |
| ▸ | JAK1 | P23458 | 5/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21344756 | 0.92 | ALDH1A1 (0.33) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL21344717 | 0.92 | KDM4E (0.34) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL24092256 | 0.86 | CYP2D6 (0.34) | ALDH1A1MEN1KMT2AMAPK1CYP3A4 | |
| SCHEMBL24426494 | 0.83 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2A | |
| SCHEMBL22345592 | 0.82 | GPR183 (0.41) | — | |
| SCHEMBL21344867 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MAPK1CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL29695286 | 0.81 | SMN1; SMN2 (0.34) | ALDH1A1KDM4EKMT2AL3MBTL1MAPK1 | |
| SCHEMBL21344868 | 0.81 | MAPK1 (0.39) | ALDH1A1MAPK1CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL24426556 | 0.81 | — | — | |
| SCHEMBL21285244 | 0.80 | YAP1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3762378-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-18 | — | — | EP | disclosed |