Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24426669 | 0.77 | ALDH1A1 (0.39) | HDAC6HPGDSMN1; SMN2MAPTACHE | |
| SCHEMBL19670114 | 0.76 | KCNK3 (0.42) | PARP1HDAC8HDAC6SMN1; SMN2KMT2A | |
| SCHEMBL18231528 | 0.76 | PARP1 (0.52) | PARP1HDAC8HDAC6HPGDSMN1; SMN2 | |
| SCHEMBL14344773 | 0.72 | PARP1 (0.52) | PARP1HDAC8HDAC6HPGDSMN1; SMN2 | |
| SCHEMBL24426611 | 0.71 | KDM4E (0.47) | HPGDSMN1; SMN2MAPTTDP1KMT2A | |
| SCHEMBL18132904 | 0.70 | PARP1 (0.42) | PARP1HDAC8HDAC6HPGDSMN1; SMN2 | |
| SCHEMBL3759037 | 0.70 | PARP1 (0.54) | PARP1HDAC8HDAC6HPGDSMN1; SMN2 | |
| SCHEMBL19497030 | 0.69 | PARP1 (0.48) | PARP1HDAC8HDAC6HPGDSMN1; SMN2 | |
| SCHEMBL20998883 | 0.69 | TDP1 (0.37) | PARP1HDAC8HDAC6HPGDSMN1; SMN2 | |
| SCHEMBL21572675 | 0.69 | PARP1 (0.41) | PARP1HDAC8HDAC6HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998107-A1 | METHOD FOR PRODUCING INSULIN-PRODUCING CELL USING DIHYDROINDOLIZINONE DERIVATIVES | Tokyo Institute of Technology (JP) | 2022-05-18 | — | — | EP | disclosed |