Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24426635 | 0.71 | PARP1 (0.43) | KDM4EHPGDSMN1; SMN2MEN1TP53 | |
| SCHEMBL14421309 | 0.70 | GABBR2 (0.45) | KDM4EHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL24426669 | 0.69 | ALDH1A1 (0.39) | HPGDALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL22703294 | 0.69 | ALDH1A1 (0.46) | KDM4EHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8713874 | 0.69 | CES2 (0.68) | KDM4EHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3399368 | 0.69 | F2 (0.63) | KDM4EHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8222675 | 0.68 | F2 (0.57) | KDM4EHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL16309346 | 0.68 | CES2 (0.67) | KDM4EHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL2837486 | 0.67 | CES2 (0.65) | KDM4EHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8242356 | 0.66 | CES2 (0.58) | KDM4EHPGDALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998107-A1 | METHOD FOR PRODUCING INSULIN-PRODUCING CELL USING DIHYDROINDOLIZINONE DERIVATIVES | Tokyo Institute of Technology (JP) | 2022-05-18 | — | — | EP | disclosed |