Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | AKT2 | P31751 | 3/20 | 0.44 |
| ▸ | AKT1 | P31749 | 3/20 | 0.44 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18962609 | 0.79 | LMNA (0.45) | CYP3A4CYP2C19GSK3BLMNA | |
| SCHEMBL1764806 | 0.77 | DRD2 (0.64) | DRD2AKT2AKT1AKT3OPRM1 | |
| SCHEMBL1977652 | 0.71 | OPRM1 (0.77) | DRD2AKT2AKT1AKT3OPRM1 | |
| SCHEMBL1978830 | 0.70 | AKT2 (0.55) | DRD2AKT2AKT1AKT3OPRM1 | |
| Hydrochloric Acid SCHEMBL1764619 | 0.70 | OPRM1 (0.74) | DRD2AKT2AKT1AKT3OPRM1 | |
| SCHEMBL12346688 | 0.70 | OPRM1 (0.58) | DRD2AKT2AKT1AKT3OPRM1 | |
| SCHEMBL1765209 | 0.70 | AKT2 (0.55) | DRD2AKT2AKT1AKT3OPRM1 | |
| SCHEMBL4071111 | 0.69 | DRD2 (0.54) | DRD2AKT2AKT1AKT3OPRM1 | |
| Hydrochloric Acid SCHEMBL1978889 | 0.68 | AKT2 (0.54) | DRD2AKT2AKT1AKT3OPRM1 | |
| SCHEMBL1980179 | 0.67 | AKT2 (0.52) | DRD2AKT2AKT1AKT3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998107-A1 | METHOD FOR PRODUCING INSULIN-PRODUCING CELL USING DIHYDROINDOLIZINONE DERIVATIVES | Tokyo Institute of Technology (JP) | 2022-05-18 | — | — | EP | disclosed |