Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.63 |
| ▸ | POLB | P06746 | 5/20 | 0.63 |
| ▸ | CHD1L | Q86WJ1 | 1/20 | 0.63 |
| ▸ | PARP9 | Q8IXQ6 | 1/20 | 0.63 |
| ▸ | CASP6 | P55212 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21571475 | 0.83 | POLB (0.67) | TDP1POLBCHD1LPARP9CASP6 | |
| SCHEMBL20353975 | 0.81 | POLB (0.78) | TDP1POLBCHD1LPARP9CASP6 | |
| SCHEMBL24426885 | 0.80 | POLB (0.56) | TDP1POLBCHD1LPARP9CASP6 | |
| SCHEMBL681883 | 0.78 | POLB (1.00) | TDP1POLBCHD1LPARP9CASP6 | |
| SCHEMBL20339087 | 0.77 | MAPT (0.68) | TDP1POLBCHD1LPARP9CASP6 | |
| SCHEMBL21571479 | 0.73 | POLB (0.64) | TDP1POLBCHD1LPARP9CASP6 | |
| SCHEMBL20339085 | 0.71 | TP53 (0.66) | POLBMEN1KMT2AALDH1A1FABP4 | |
| SCHEMBL918590 | 0.69 | MEN1 (0.79) | TDP1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL15281318 | 0.69 | ALDH1A1 (0.93) | TDP1POLBCHD1LPARP9CASP6 | |
| SCHEMBL16817311 | 0.69 | FABP4 (1.00) | FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562818-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2022-05-18 | — | — | EP | disclosed |