Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24427050 | 0.86 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2LMNAMAPTKDM4E | |
| SCHEMBL24427079 | 0.72 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL14528489 | 0.71 | FABP4 (0.56) | ALDH1A1SMN1; SMN2MAPTKDM4EFABP4 | |
| SCHEMBL5536167 | 0.69 | TLR7 (0.53) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1301722 | 0.69 | TLR7 (0.72) | — | |
| SCHEMBL24427048 | 0.69 | TLR7 (0.39) | ALDH1A1SMN1; SMN2LMNAKDM4EFABP4 | |
| SCHEMBL24427104 | 0.69 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNAMAPTKDM4E | |
| SCHEMBL22863463 | 0.68 | TLR7 (0.45) | ALDH1A1SMN1; SMN2LMNAMAPTKDM4E | |
| SCHEMBL22863456 | 0.68 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL22863470 | 0.68 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2LMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998255-A1 | SMALL-MOLECULE REGULATOR OF TLR8 | Tsinghua University (CN) | 2022-05-18 | — | — | EP | disclosed |